Literature DB >> 6698957

Anti-protein kinase NII antibodies in rheumatic autoimmune diseases.

D A Stetler, K M Rose, M E Wenger, C M Berlin, S T Jacob.   

Abstract

Antibodies against nuclear protein kinase NII were detected by radioimmunoassay in the sera of patients with systemic lupus erythematosus and mixed connective tissue disease but not in sera from normal individuals or from patients with rheumatoid arthritis. Immunoglobulins derived from sera containing the anti-kinase antibodies inhibited the activity of protein kinase NII in vitro but had no effect on the activity of cytoplasmic cyclic AMP-dependent protein kinase.

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Year:  1984        PMID： 6698957

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  4 in total

1.  Antibodies against nuclear poly(A) polymerases in rheumatic autoimmune diseases.

Authors:  D A Stetler; M Reichlin; C M Berlin; S T Jacob
Journal:  J Clin Immunol       Date:  1987-01       Impact factor: 8.317

Review 2.  Antinuclear antibody profiles in relation to specific disease manifestations of systemic lupus erythematosus.

Authors:  A J Swaak; V Huysen; J C Nossent; R J Smeenk
Journal:  Clin Rheumatol       Date:  1990-03       Impact factor: 2.980

3.  Immunization of rabbits with purified RNA polymerase I induces a distinct population of antibodies against nucleic acids as well as anti-RNA polymerase I antibodies, both characteristic of systemic lupus erythematosus.

Authors:  D A Stetler; S T Jacob
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

4.  Anti-RNA polymerase I antibodies in sera of MRL lpr/lpr and MRL +/+ autoimmune mice. Correlation of antibody production with delayed onset of lupus-like disease in MRL +/+ mice.

Authors:  D A Stetler; D E Sipes; S T Jacob
Journal:  J Exp Med       Date:  1985-12-01       Impact factor: 14.307
  4 in total

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