| Literature DB >> 6698179 |
Abstract
The endoperoxide analogs known as U-46619 and U-44069 significantly enhanced the carcinoma formation and cellular atypicality initiated by a chemical carcinogen in mice. Studies of DNA radioactivity demonstrated that endoperoxides exerted their cocarcinogenic action by stimulating DNA synthesis. Thus, they play an important role in tumor cell proliferation.Entities:
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Year: 1984 PMID： 6698179 DOI： 10.1007/bf01963604
Source DB: PubMed Journal: Experientia ISSN： 0014-4754