Literature DB >> 6698122

Cathepsin D stimulates DNA synthesis and mitosis in mouse liver in vivo.

M Morioka, H Terayama.   

Abstract

Effects of a single intraperitoneal injection of cathepsin D (CatD) on DNA synthesis and mitosis in the mouse liver and kidney were investigated. Twenty micrograms of catD induced a significant stimulation of DNA synthesis in the liver, but not in the kidney, in a dose-dependent fashion and with a peak activity at 38 h after the injection. CatD also stimulated liver mitosis, with a peak value at 44 h after the injection.

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Year:  1984        PMID： 6698122     DOI： 10.1016/0014-4827(84)90377-x

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN： 0014-4827            Impact factor:   3.905


  4 in total

1.  Immunolocalization of cathepsin D in pneumocytes of normal human lung and in pulmonary fibrosis.

Authors:  M Kasper; P Lackie; M Haase; D Schuh; M Müller
Journal:  Virchows Arch       Date:  1996-07       Impact factor: 4.064

2.  Healing of focal injury in the rat liver.

Authors:  K Ogawa; J Suzuki; M Narasaki; M Mori
Journal:  Am J Pathol       Date:  1985-04       Impact factor: 4.307

3.  Hepatotrophic activity in mouse serum infected with plerocercoids of Spirometra erinacei.

Authors:  T Tsuboi; M Torii; K Oka; K Hirai
Journal:  Parasitol Res       Date:  1994       Impact factor: 2.289

Review 4.  Cathepsin D expression levels in nongynecological solid tumors: clinical and therapeutic implications.

Authors:  Gaetano Leto; Francesca M Tumminello; Marilena Crescimanno; Carla Flandina; Nicola Gebbia
Journal:  Clin Exp Metastasis       Date:  2004       Impact factor: 5.150
  4 in total

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