Literature DB >> 6695194

Dioxin in soil: bioavailability after ingestion by rats and guinea pigs.

E E McConnell, G W Lucier, R C Rumbaugh, P W Albro, D J Harvan, J R Hass, M W Harris.   

Abstract

Soil environmentally contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) was given by gavage to guinea pigs and rats. The development of a characteristic clinicopathologic syndrome in guinea pigs, the induction of aryl hydrocarbon hydroxylase in rats, and the presence of TCDD in the livers of both species show that TCDD in soil exhibits high biological availability after ingestion.

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Year:  1984        PMID： 6695194     DOI： 10.1126/science.6695194

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Differences in kinetics of pure and soil-adsorbed toluene in orally exposed male rats.

Authors:  R M Turkall; G A Skowronski; M S Abdel-Rahman
Journal:  Arch Environ Contam Toxicol       Date:  1991-02       Impact factor: 2.804

2.  Immunotoxic effects of exposure of rats to xenobiotics via maternal lactation. Part I 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Authors:  J S Badesha; G Maliji; B Flaks
Journal:  Int J Exp Pathol       Date:  1995-12       Impact factor: 1.925

3.  Reproductive studies of C57B/6 male mice treated with TCDD-contaminated soils from a 2,4,5-trichlorophenoxyacetic acid manufacturing site.

Authors:  T H Umbreit; E J Hesse; M A Gallo
Journal:  Arch Environ Contam Toxicol       Date:  1988-03       Impact factor: 2.804

4.  Soil adsorption alters kinetics and bioavailability of benzene in orally exposed male rats.

Authors:  R M Turkall; G Skowronski; S Gerges; S Von Hagen; M S Abdel-Rahman
Journal:  Arch Environ Contam Toxicol       Date:  1988-03       Impact factor: 2.804

5.  Oral bioavailability of aged polychlorinated biphenyl residues contained in soil.

Authors:  G F Fries; G S Marrow; C J Somich
Journal:  Bull Environ Contam Toxicol       Date:  1989-11       Impact factor: 2.151

Review 6.  Long-term carcinogenesis studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin and hexachlorodibenzo-p-dioxins.

Authors:  J E Huff; A G Salmon; N K Hooper; L Zeise
Journal:  Cell Biol Toxicol       Date:  1991-01       Impact factor: 6.691

7.  Reproductive toxicity in female mice of dioxin-contaminated soils from a 2,4,5-trichlorophenoxyacetic acid manufacturing site.

Authors:  T H Umbreit; E J Hesse; M A Gallo
Journal:  Arch Environ Contam Toxicol       Date:  1987-07       Impact factor: 2.804

8.  Distribution of 2,3,7,8-tetrachlorodibenzo-p-dioxin in human whole blood and its association with, and extractability from, lipoproteins.

Authors:  L O Henderson; D G Patterson
Journal:  Bull Environ Contam Toxicol       Date:  1988-04       Impact factor: 2.151

9.  Dioxin in Missouri: 1971-1983.

Authors:  R L Powell
Journal:  Bull Environ Contam Toxicol       Date:  1984-12       Impact factor: 2.151

Review 10.  Immunologic effects of TCDD exposure in humans.

Authors:  A P Knutsen
Journal:  Bull Environ Contam Toxicol       Date:  1984-12       Impact factor: 2.151
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