Literature DB >> 6693396

The covalent structure of hepatic microsomal epoxide hydrolase. II. The complete amino acid sequence.

F S Heinemann, J Ozols.   

Abstract

The complete amino acid sequence of hepatic microsomal epoxide hydrolase has been determined. The protein contains 455 amino acid residues in a single polypeptide chain and has Mr = 52,691. Peptides from selective chemical and proteolytic cleavages were isolated by a combination of gel filtration and high performance liquid chromatography and sequenced by automated Edman degradation. Overlapping peptide sequences were used to deduce the complete sequence. This is the first epoxide hydrolase and the third microsomal enzyme for which the complete sequence has been determined.

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Year:  1984        PMID: 6693396

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  5 in total

1.  Molecular cloning and amino acid sequence of leukotriene A4 hydrolase.

Authors:  C D Funk; O Rådmark; J Y Fu; T Matsumoto; H Jörnvall; T Shimizu; B Samuelsson
Journal:  Proc Natl Acad Sci U S A       Date:  1987-10       Impact factor: 11.205

Review 2.  Hexokinase receptors: preferential enzyme binding in normal cells to nonmitochondrial sites and in transformed cells to mitochondrial sites.

Authors:  K K Arora; D M Parry; P L Pedersen
Journal:  J Bioenerg Biomembr       Date:  1992-02       Impact factor: 2.945

3.  Cloning of 1,2-dichloroethane degradation genes of Xanthobacter autotrophicus GJ10 and expression and sequencing of the dhlA gene.

Authors:  D B Janssen; F Pries; J van der Ploeg; B Kazemier; P Terpstra; B Witholt
Journal:  J Bacteriol       Date:  1989-12       Impact factor: 3.490

4.  Isolation and the complete amino acid sequence of lumenal endoplasmic reticulum glucose-6-phosphate dehydrogenase.

Authors:  J Ozols
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205

5.  Epoxide hydrolase is a marker for the smooth endoplasmic reticulum in rat liver.

Authors:  M M Galteau; B Antoine; H Reggio
Journal:  EMBO J       Date:  1985-11       Impact factor: 11.598

  5 in total

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