Literature DB >> 6692918

Decreased rate of fatty acid synthesis in brown adipose tissue of hypothalamic obese rats.

M Saito, T Shimazu.   

Abstract

Obese rats with lesions of the ventromedial hypothalamus (VMH) exhibited a 3-fold increase in the wet weight of interscapular brown adipose tissue (IBAT), due to an increased triglyceride content, compared with lean controls. The rate of lipogenesis in IBAT was much higher than that in white adipose tissues in control rats, but decreased greatly in rats with VMH lesions and approximated the value in white adipose tissues. It was suggested that thermogenesis in BAT was impaired after VMH lesions by decreasing triglyceride turnover in BAT.

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Year:  1984        PMID： 6692918     DOI： 10.1016/0014-5793(84)80062-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Comparison of DNA synthesis in white and brown adipose tissue in rats with ventromedial hypothalamic lesions.

Authors:  T Kiba; K Tanaka; M Hoshino; K Numata; S Inoue
Journal:  Pflugers Arch       Date:  1993-07       Impact factor: 3.657

2.  Glucose utilization in vivo and insulin-sensitivity of rat brown adipose tissue in various physiological and pathological conditions.

Authors:  P Ferré; A F Burnol; A Leturque; J Terretaz; L Penicaud; B Jeanrenaud; J Girard
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

3.  Changes in the lipogenic response to feeding of liver, white adipose tissue and brown adipose tissue during the development of obesity in the gold-thioglucose-injected mouse.

Authors:  G J Cooney; M A Vanner; J L Nicks; P F Williams; I D Caterson
Journal:  Biochem J       Date:  1989-05-01       Impact factor: 3.857

4.  P110β in the ventromedial hypothalamus regulates glucose and energy metabolism.

Authors:  Teppei Fujikawa; Yun-Hee Choi; Dong Joo Yang; Dong Min Shin; Jose Donato; Daisuke Kohno; Charlotte E Lee; Carol F Elias; Syann Lee; Ki Woo Kim
Journal:  Exp Mol Med       Date:  2019-04-26       Impact factor: 8.718
  4 in total

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