Literature DB >> 6691933

Occupational exposure to hydrazine and subsequent risk of cancer.

N Wald, J Boreham, R Doll, J Bonsall.   

Abstract

Four hundred and twenty seven men with varying degrees of occupational exposure to hydrazine, a weak animal carcinogen, were studied to see if they provided any evidence of carcinogenicity to man. The observed mortality was close to that expected for lung cancer, other cancers, and all other causes, irrespective of the level of exposure. There were 49 deaths (61.47 expected) from all causes including five deaths from lung cancer (6.65 expected). The results show that no obvious hazards associated with hydrazine exposure have yet appeared but because of the small number of men studied they can only exclude gross hazards.

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Year:  1984        PMID: 6691933      PMCID: PMC1009232          DOI: 10.1136/oem.41.1.31

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN: 0007-1072


  7 in total

1.  Hepatomas in CBA/Cb/Se mice and liver lesions in golden hamsters induced by hydrazine sulfate.

Authors:  C Biancifiori
Journal:  J Natl Cancer Inst       Date:  1970-04       Impact factor: 13.506

2.  Tumorigenesis studies with 1,2-dimethylhydrazine dihydrochloride, hydrazine sulfate, and isonicotinic acid in golden hamsters.

Authors:  B Toth
Journal:  Cancer Res       Date:  1972-04       Impact factor: 12.701

3.  Hepatic carcinogenesis in CBA-Cb-Se mice and Cb-Se rats by isonicotinic acid hydrazide and hydrazine sulfate.

Authors:  L Severi; C Biancifiori
Journal:  J Natl Cancer Inst       Date:  1968-08       Impact factor: 13.506

4.  Tumor-inducing effect of hydrazine in mice.

Authors:  J Juhász; J Baló; B Szende
Journal:  Nature       Date:  1966-06-25       Impact factor: 49.962

5.  Hydrazine.

Authors:  F J Roe
Journal:  Ann Occup Hyg       Date:  1978-12

6.  Pulmonary tumours in rats induced by oral hydrazine sulphate.

Authors:  C Biancifiori; F E Giornelli-Santilli; U Milia; L Severi
Journal:  Nature       Date:  1966-10-22       Impact factor: 49.962

7.  Lung tumour incidence in mice treated with hydrazine sulphate.

Authors:  S V Bhide; R A D'Souza; M M Sawai; K J Ranadive
Journal:  Int J Cancer       Date:  1976-10-15       Impact factor: 7.396

  7 in total
  2 in total

1.  Occupational exposure to hydrazine and subsequent risk of cancer.

Authors:  J Morris; J W Densem; N J Wald; R Doll
Journal:  Occup Environ Med       Date:  1995-01       Impact factor: 4.402

2.  Occupational Exposure to Hydrazine and Subsequent Risk of Lung Cancer: 50-Year Follow-Up.

Authors:  Joan K Morris; Nicholas J Wald; Anna L Springett
Journal:  PLoS One       Date:  2015-09-22       Impact factor: 3.240

  2 in total

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