Literature DB >> 6691458

Erythrocyte catechol O-methyltransferase activity in schizophrenia: analysis of family data.

M Baron, R Gruen, M Levitt, C Hunter, L Asnis.   

Abstract

The authors determined the erythrocyte catechol O-methyltransferase (COMT) activity of 38 chronic schizophrenic patients, 69 of their first-degree relatives, and 39 normal controls. COMT activity did not distinguish patients from controls. Within families, COMT activity was not associated with schizophrenia spectrum disorders. The data suggest that COMT activity is not an indicator of vulnerability to schizophrenia.

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Year:  1984        PMID: 6691458     DOI: 10.1176/ajp.141.1.29

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  1 in total

Review 1.  The role of candidate genes in the etiology of schizophrenia.

Authors:  K C Murphy; P McGuffin
Journal:  Mol Med       Date:  1996-11       Impact factor: 6.354

  1 in total

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