| Literature DB >> 6690054 |
M L Friedlander, D W Hedley, I W Taylor, P Russell, A S Coates, M H Tattersall.
Abstract
Tumor cellular DNA content was measured by flow cytometry in 91 patients with advanced ovarian cancer, using a new and simple technique which allows archival paraffin-embedded tissue to be studied; 69% of the tumors were aneuploid, and 31% were diploid. Tumor ploidy was shown by multivariate Cox model analysis to be an independent prognostic variable and the major determinant of survival. Patients with diploid tumors survived significantly longer than did those with aneuploid tumors (p much less than 0.0001; X2 = 25.44; d.f. = 1).Entities:
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Year: 1984 PMID： 6690054
Source DB: PubMed Journal: Cancer Res ISSN： 0008-5472 Impact factor: 12.701