Literature DB >> 6689

The narcotic discriminative stimulus complex: relation to analgesic activity.

F C Colpaert, C J Niemegeers, P A Janssen.   

Abstract

The ability of drugs to produce the narcotic discriminative stimulus complex is found to be highly correlated with their analgesic activity; in contrast, no relation with their antidiarrhoeal activity is evident. The findings suggest that the narcotic discriminative stimulus complex is a centrally mediated effect of narcotic drugs.

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Year:  1976        PMID: 6689     DOI: 10.1111/j.2042-7158.1976.tb04127.x

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  5 in total

Review 1.  Pathogenesis and pharmacology of diarrhea.

Authors:  L Ooms; A Degryse
Journal:  Vet Res Commun       Date:  1986-09       Impact factor: 2.459

2.  Narcotic cuing and analgesic activity of narcotic analgesics: associative and dissociative characteristics.

Authors:  F C Colpaert; C J Niemegeers; P A Janssen
Journal:  Psychopharmacology (Berl)       Date:  1978-04-14       Impact factor: 4.530

Review 3.  Role of training dose in drug discrimination: a review.

Authors:  Ian P Stolerman; Emma Childs; Matthew M Ford; Kathleen A Grant
Journal:  Behav Pharmacol       Date:  2011-09       Impact factor: 2.293

4.  Opioid antinociception, tolerance and dependence: interactions with the N-methyl-D-aspartate system in mice.

Authors:  Linda A Dykstra; Bradford D Fischer; Rebecca E Balter; Fredrick E Henry; Karl T Schmidt; Laurence L Miller
Journal:  Behav Pharmacol       Date:  2011-09       Impact factor: 2.293

5.  Tolerance to morphine-produced discriminative stimuli and analgesia.

Authors:  S Miksic; H Lal
Journal:  Psychopharmacology (Berl)       Date:  1977-10-20       Impact factor: 4.530

  5 in total

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