Literature DB >> 6688804

A new antitumor antibiotic, awamycin.

I Umezawa, H Oka, K Komiyama, K Hagiwara, S Tomisaka, T Miyano.   

Abstract

A new antibiotic, awamycin, was isolated from the culture broth of Streptomyces sp. No. 80-217. It appeared to belong to the quinone indicator group from results of physicochemical studies and has the empirical formula C38H49NO12S. This antibiotic possessed antibacterial and antitumor activities against Gram-positive bacteria and experimental murine tumors. The antibiotic also showed direct cytotoxic activity against HeLa cells in vitro.

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Year:  1983        PMID: 6688804     DOI: 10.7164/antibiotics.36.1144

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  1 in total

1.  Two sulfur-containing ansamycin antibiotics from Streptomyces albolongus.

Authors:  S Tanida; S Shinagwa; M Takizawa; T Takahashi; S Harada; T Hasegawa
Journal:  Experientia       Date:  1986-10-15
  1 in total

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