Literature DB >> 6687853

Microcomputer based pharmacokinetic programs for calculating absorption rate.

K K Chan, K Wnuck.   

Abstract

A package of microcomputer based pharmacokinetic programs for evaluating in vivo absorption rate has been developed. The following programs are included in the package: TEXT FILE (program to create a data file which can be accessed by all pharmacokinetic programs), WN12GT (Wagner-Nelson method), LOO (modified Loo-Riegelman method), DECON (deconvolution method), and MODMOMT (method of statistical moments). All programs were tested with data obtained from standard texts or original articles. This package of programs designed to be interactive, flexible, and easily used by a novice. The modular design facilitates modification, upkeep and accommodation of new methods of calculation.

Mesh：

Substances：

Year:  1983        PMID： 6687853     DOI： 10.1016/0010-468x(83)90005-3

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN： 0010-468X


  7 in total

1.  Hemoperfusion in acute camphor poisoning.

Authors:  C Köppel; F Martens; T Schirop; K Ibe
Journal:  Intensive Care Med       Date:  1988       Impact factor: 17.440

2.  An experimental model for measuring middle ear antimicrobial drug penetration in otitis media.

Authors:  G H Jossart; G R Erdmann; D G Levitt; P Kucera; C T Le; S K Juhn; G S Giebink; D M Canafax
Journal:  Pharm Res       Date:  1990-12       Impact factor: 4.200

3.  Pharmacokinetics and antiarrhythmic efficacy of intravenous ajmaline in ventricular arrhythmia of acute onset.

Authors:  C Köppel; A Wagemann; F Martens
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1989 Apr-Jun       Impact factor: 2.441

4.  Chlormezanone plasma and blood levels in patients after single and repeated oral doses and after suicidal drug overdose.

Authors:  C Köppel; J Kristinsson; A Wagemann; J Tenczer; F Martens
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1991 Jan-Mar       Impact factor: 2.441

5.  High-performance liquid chromatographic determination of 2',3'-didehydro-3'-deoxythymidine (d4T) in human and rabbit plasma and urine and its application to pharmacokinetic studies in the rabbit.

Authors:  S L Wong; R J Sawchuk
Journal:  Pharm Res       Date:  1991-05       Impact factor: 4.200

6.  Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics.

Authors:  D M Canafax; H Russlie; M J Lovdahl; G R Erdmann; C T Le; G S Giebink
Journal:  Pharm Res       Date:  1994-06       Impact factor: 4.200

7.  Liposomal formulation eliminates acute toxicity and pump incompatibility of parenteral cyclosporine.

Authors:  S A Gruber; S Venkataram; D M Canafax; R J Cipolle; L Bowers; D Elsberry; M McGuiggan; P E Hynes; J A Ritz; F H Gould
Journal:  Pharm Res       Date:  1989-07       Impact factor: 4.200
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.