Literature DB >> 6687562

Clones from cultured, B16 mouse-melanoma cells resistant to wheat-germ agglutinin and with altered production of mucin-type glycoproteins.

L H Lin, J L Stern, E A Davidson.   

Abstract

Several clones resistant to wheat-germ-agglutinin toxicity were isolated from B16 mouse-melanoma cells. The resistance may be explained in part by fewer binding sites for the agglutinin on the variant lines; the total, cellular sialic acid content appeared somewhat reduced. Analysis of cell glycoproteins indicated a decreased content of sialic acid in one glycoconjugate that binds to wheat-germ agglutinin and has O-linked oligosaccharides.

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Year:  1983        PMID: 6687562     DOI: 10.1016/0008-6215(83)88310-4

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN: 0008-6215            Impact factor:   2.104


  3 in total

1.  Molecular identification of lectin binding sites differentiating related low and high metastatic murine lymphomas.

Authors:  E Lang; V Schirrmacher; P Altevogt
Journal:  Clin Exp Metastasis       Date:  1988 Jan-Feb       Impact factor: 5.150

2.  Decreased tumorigenicity correlates with expression of altered cell surface carbohydrates in Lec9 CHO cells.

Authors:  J Ripka; S Shin; P Stanley
Journal:  Mol Cell Biol       Date:  1986-04       Impact factor: 4.272

Review 3.  Challenge to the suppression of tumor growth by the β4-galactosyltransferase genes.

Authors:  Kiyoshi Furukawa
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2015       Impact factor: 3.493

  3 in total

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