Literature DB >> 6686676

Cataleptogenic effect of haloperidol, chlorpromazine and morphine in developing rats.

R Brus, T Krzemiński, J Piguła.   

Abstract

The intensity of catalepsy produced by haloperidol (0.5 mg/kg), chlorpromazine (10 mg/kg) and morphine (20 mg/kg) given ip was tested in male Wistar rats of age between 3 weeks and 6 months. The cataleptic response was most expressed in the youngest animals, and decreased with age. The results indicate that young rats show higher reactivity of central dopaminergic receptors to the investigated drugs.

Entities:  

Mesh:

Substances:

Year:  1983        PMID: 6686676

Source DB:  PubMed          Journal:  Pol J Pharmacol Pharm        ISSN: 0301-0244


  3 in total

1.  Behavioral effects of dopamine receptor inactivation during the adolescent period: age-dependent changes in dorsal striatal D2(High) receptors.

Authors:  Sanders A McDougall; Joseph M Valentine; Ashley E Gonzalez; Danielle E Humphrey; Crystal B Widarma; Cynthia A Crawford
Journal:  Psychopharmacology (Berl)       Date:  2013-11-28       Impact factor: 4.530

2.  Decreasing sensitivity to neuroleptic agents in developing rats; evidence for a pharmacodynamic factor.

Authors:  A Campbell; R J Baldessarini; M H Teicher
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

3.  Importance of dopaminergic neurotransmission for the RU 24969-induced locomotor activity of male and female rats during the preweanling period.

Authors:  Sanders A McDougall; Nazaret R Montejano; Ginny I Park; Jasmine A M Robinson
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2020-11-18       Impact factor: 3.000

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.