| Literature DB >> 6686159 |
G Thibault, R Garcia, N G Seidah, C Lazure, M Cantin, M Chrétien, J Genest.
Abstract
A natriuretic factor has been described in the specific granules of rat atria. We have purified three factors which seem to be low-Mr peptides. They have been purified by means of acid extraction, octadecyl Sep-Pak cartridges, and chromatography on Bio-Gel P-10, CM Bio-Gel A, Mono S and reverse-phase high-performance liquid chromatography columns. The factors contain 26, 31 and 33 amino acids and may have been partially degraded during isolation. They are all 3 biologically active and the shorter one is the most active with a specific activity of 450 000 units/mg.Entities:
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Year: 1983 PMID： 6686159 DOI： 10.1016/0014-5793(83)80303-2
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124