Literature DB >> 6685904

Selenium efficiently depressed toxic side effect of cis-diamminedichloroplatinum.

A Naganuma, M Satoh, M Yokoyama, N Imura.   

Abstract

Effect of selenium on toxic side effects of cis-diamminedichloroplatinum (Cisplatin; CDDP) which is a potent anticancer drug containing platinum was examined. Remarkable protective effects of selenium against lethal and renal toxicity of CDDP were observed when selenite was administered to mice once a day after single injection of lethal dose of CDDP. On the other hand antitumor activity of CDDP was hardly depressed by selenite.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6685904

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN： 0034-5164


  7 in total

1.  Correlation of levels of Pt and Se in rats treated simultaneously with cisplatin and sodium selenite.

Authors:  H Sakurai; K Tsuchiya
Journal:  Naturwissenschaften       Date:  1988-08

2.  Chemotherapy and trace element levels in blood and tissue of rats implanted with prostate tumor cells.

Authors:  K Kuehn; U Dunzendorfer; W F Whitmore; G N Schrauzer
Journal:  Biol Trace Elem Res       Date:  1985-12       Impact factor: 3.738

3.  Effect of coadministration of selenite on the toxicity and antitumor activity of cis-diamminedichloroplatinum (II) given repeatedly to mice.

Authors:  M Satoh; A Naganuma; N Imura
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

4.  Effect of bismuth nitrate given in combination with cis-diamminedichloroplatinum(II) on the antitumor activity and renal toxicity of the latter in nude mice inoculated with human bladder tumor.

Authors:  Y Kondo; M Satoh; N Imura; M Akimoto
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

5.  Effect of pharmacologic doses of zinc on the therapeutic index of brain tumor chemotherapy with carmustine.

Authors:  N Roosen; F Doz; K L Yeomans; D V Dougherty; M L Rosenblum
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

Review 6.  Cisplatin-Induced Nephrotoxicity; Protective Supplements and Gender Differences

Authors:  Mehdi Nematbakhsh; Zahra Pezeshki; Fatemeh Eshraghi Jazi; Bahar Mazaheri; Maryam Moeini; Tahereh Safari; Fariba Azarkish; Fatemeh Moslemi; Maryam Maleki; Alireza Rezaei; Shadan Saberi; Aghdas Dehghani; Maryam Malek; Azam Mansouri; Marzieh Ghasemi; Farzaneh Zeinali; Zohreh Zamani; Mitra Navidi; Sima Jilanchi; Soheyla Shirdavani; Farzaneh Ashrafi
Journal:  Asian Pac J Cancer Prev       Date:  2017-02-01

7.  The effects of co-administration of selenium and cis-platin (CDDP) on CDDP-induced toxicity and antitumour activity.

Authors:  K Ohkawa; Y Tsukada; H Dohzono; K Koike; Y Terashima
Journal:  Br J Cancer       Date:  1988-07       Impact factor: 7.640
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.