Literature DB >> 6685804

Cis-platinum ototoxicity: clinical experience and temporal bone histopathology.

M Strauss, J Towfighi, S Lord, A Lipton, H A Harvey, B Brown.   

Abstract

A clinical and pathologic study of cis-platinum ototoxicity was performed. Twenty-four patients treated with cis-platinum for head and neck cancer were studied prospectively. Post cis-platinum hearing losses were subclinical, detected in 25% of patients, isolated to 4 and 8 kHz, and did not exceed 25 dB at any frequency. Temporal bones from a 9-year-old with frontal lobe astrocytoma and with cis-platinum ototoxicity were studied with routine and special techniques to elucidate oto and neurotoxicity. Degenerative changes in the outer hair cells in the lower turns of the cochlea, in the spiral ganglion, and cochlear nerve were the most striking findings.

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Year:  1983        PMID： 6685804     DOI： 10.1288/00005537-198312000-00007

Source DB:  PubMed          Journal:  Laryngoscope        ISSN： 0023-852X            Impact factor:   3.325


  15 in total

1.  Cisplatin ototoxicity and otoprotection with sodium salicylate.

Authors:  Miguel Angelo Hyppolito; José Antonio A de Oliveira; Maria Rossato
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-06-07       Impact factor: 2.503

2.  Preincision complex-I from the excision nuclease reaction among cochlear spiral limbus and outer hair cells.

Authors:  O'neil W Guthrie
Journal:  J Mol Histol       Date:  2008-11-01       Impact factor: 2.611

3.  Comparison of cochlear cell death caused by cisplatin, alone and in combination with furosemide.

Authors:  Li Xia; Zhengnong Chen; Kaiming Su; Shankai Yin; Jian Wang
Journal:  Toxicol Pathol       Date:  2013-04-02       Impact factor: 1.902

4.  Very high-dose cisplatin-induced ototoxicity: a preliminary report on early and long-term effects.

Authors:  C F Pollera; P Marolla; M Nardi; F Ameglio; L Cozzo; F Bevere
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

5.  Cisplatin-induced ototoxicity: audiometric findings and experimental cochlear pathology.

Authors:  K Böheim; E Bichler
Journal:  Arch Otorhinolaryngol       Date:  1985

Review 6.  Cisplatin and aminoglycoside antibiotics: hearing loss and its prevention.

Authors:  Jochen Schacht; Andra E Talaska; Leonard P Rybak
Journal:  Anat Rec (Hoboken)       Date:  2012-10-08       Impact factor: 2.064

7.  Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice.

Authors:  Robert N Rainey; Sum-Yan Ng; Juan Llamas; Gijsbertus T J van der Horst; Neil Segil
Journal:  J Neurosci       Date:  2016-04-27       Impact factor: 6.167

Review 8.  Experimental, clinical and preventive aspects of ototoxicity.

Authors:  A A Chiodo; P W Alberti
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

Review 9.  Comparative adverse effect profiles of platinum drugs.

Authors:  M J McKeage
Journal:  Drug Saf       Date:  1995-10       Impact factor: 5.606

10.  Survival and late toxicities following concurrent chemo-radiotherapy for locally advanced stage III non-small cell lung cancer: findings of a 10-year Australian single centre experience with long term clinical follow up.

Authors:  M Nazim Abbas; Adeola Ayoola; Sunita Padman; Rajiv Kumar; John Leung; Shahid Ullah; Bogda Koczwara; Shawgi Sukumaran; Ganessan Kichenadasse; Amitesh Roy; Alison M Richards; Jeffrey J Bowden; Christos S Karapetis
Journal:  J Thorac Dis       Date:  2019-10       Impact factor: 2.895
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