Literature DB >> 6684961

Erythropoietin production by a human testicular germ cell line.

J L Ascensao, F Gaylis, D Bronson, E E Fraley, E D Zanjani.   

Abstract

An established human testis germ cell line (1411-H) was found to produce significant amounts of erythropoietin (Ep), the primary regulator of erythropoiesis. Media conditioned by the 1411-H cells stimulated erythropoiesis both in vivo and in vitro. This activity was neutralized by anti-Ep. This continuous cell line provides a unique model for the study of the mechanisms of control of Ep biogenesis.

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Year:  1983        PMID： 6684961

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  4 in total

1.  The regulated expression of erythropoietin by two human hepatoma cell lines.

Authors:  M A Goldberg; G A Glass; J M Cunningham; H F Bunn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

2.  Plasma protein and apolipoprotein synthesis by human yolk sac carcinoma cells in vitro.

Authors:  R E Lanford; D L Bronson; L E Estlack; F H Wians
Journal:  In Vitro Cell Dev Biol       Date:  1991-03

3.  Studies on the role of recombinant human erythropoietin in the growth regulation of human nonhematopoietic tumor cells in vitro.

Authors:  W E Berdel; D Oberberg; B Reufi; E Thiel
Journal:  Ann Hematol       Date:  1991-07       Impact factor: 3.673

4.  Continuous production of erythropoietin by an established human renal carcinoma cell line: development of the cell line.

Authors:  J B Sherwood; D Shouval
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205
  4 in total

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