Literature DB >> 6684747

Effect of liposomal encapsulation of cis-platinum diamminodichloride in the treatment of Ehrlich ascites carcinoma.

B Sur, R R Ray, P Sur, D K Roy.   

Abstract

cis-Platinum diamminodichloride (II) encapsulated in neutral liposomes has been used to enhance the activity of the drug on Ehrlich ascites carcinoma in mice. Both in vitro and in vivo experiments have revealed that better regression in tumor growth and cure, could be achieved with a lower dose, having apparently no toxic effect, by liposomal encapsulation of the drug.

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Year:  1983        PMID： 6684747     DOI： 10.1159/000225765

Source DB:  PubMed          Journal:  Oncology        ISSN： 0030-2414            Impact factor:   2.935


  3 in total

1.  Liposomes as drug carrier system for cis-diamminedichloroplatinum (II). II. Antitumor activity in vivo, induction of drug resistance, nephrotoxicity and Pt distribution.

Authors:  P A Steerenberg; G Storm; G de Groot; A Claessen; J J Bergers; M A Franken; Q G van Hoesel; K L Wubs; W H de Jong
Journal:  Cancer Chemother Pharmacol       Date:  1988       Impact factor: 3.333

Review 2.  Advances in platinum cancer chemotherapy. Advances in the design of cisplatin analogues.

Authors:  P C Hydes; M J Russell
Journal:  Cancer Metastasis Rev       Date:  1988-04       Impact factor: 9.264

3.  Enhancement of both intracellular uptake and antitumor action of cisplatinum on human neuroblastoma cells by encapsulation in liposomes.

Authors:  Y Kamio; H Kato; T Kishikawa; T Toda; S Sasaki; J Ito; T Kato; R Tanaka
Journal:  Jpn J Cancer Res       Date:  1989-08
  3 in total

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