| Literature DB >> 6684461 |
A Romero, T Grau, A Sacristán, J A Ortiz.
Abstract
A single oral dose of 1.5 g/kg cytidine diphosphate choline (CDP-choline, citicoline, Somazina) was administered to 6 Beagle dogs daily for 6 months. After treatment period, treated animals as well as control animals were sacrificed and assessment of urinalysis, blood analysis and histopathological studies were made. Results were found within normal ranges--involving slight changes due to individual variability. It can therefore be concluded that CDP-choline does not cause any toxic effects under the chosen experimental conditions.Entities:
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Year: 1983 PMID： 6684461
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172