Literature DB >> 6684413

The resident faecal flora is determined by genetic characteristics of the host. Implications for Crohn's disease?

J P Van de Merwe, J H Stegeman, M P Hazenberg.   

Abstract

Recently, an "abnormal" faecal flora has been associated with Crohn's disease, a disease of unknown origin but with pertinent genetic predisposition. Therefore, it was investigated whether the faecal flora is under genetic influence in groups of monozygotic and dizygotic twins. Faecal floras of monozygotic twin siblings were found to be much more alike than those of dizygotic twin siblings. It is concluded that the resident faecal flora is under genetic influence and may be useful parameter to study possible genetic backgrounds of other diseases.

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Year:  1983        PMID： 6684413     DOI： 10.1007/bf00393669

Source DB:  PubMed          Journal:  Antonie Van Leeuwenhoek        ISSN： 0003-6072            Impact factor:   2.271


  6 in total

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Authors:  F Wensinck
Journal:  Antonie Van Leeuwenhoek       Date:  1975       Impact factor: 2.271

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Authors:  A HOEKSMA; K C WINKLER
Journal:  Acta Leiden       Date:  1963

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Authors:  L V Holdeman; I J Good; W E Moore
Journal:  Appl Environ Microbiol       Date:  1976-03       Impact factor: 4.792

4.  A possible role of Eubacterium and Peptostreptococcus species in the aetiology of Crohn's disease.

Authors:  J P van de Merwe; G J Mol
Journal:  Antonie Van Leeuwenhoek       Date:  1980       Impact factor: 2.271

5.  The faecal flora of patients with Crohn's disease.

Authors:  F Wensinck; P A Poppelaars-Kustermans; A M Schröder
Journal:  J Hyg (Lond)       Date:  1981-08

6.  Human fecal flora: the normal flora of 20 Japanese-Hawaiians.

Authors:  W E Moore; L V Holdeman
Journal:  Appl Microbiol       Date:  1974-05
  6 in total
  29 in total

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Authors:  K Kimura; A L McCartney; M A McConnell; G W Tannock
Journal:  Appl Environ Microbiol       Date:  1997-09       Impact factor: 4.792

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6.  Microbiota conservation and BMI signatures in adult monozygotic twins.

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8.  Healthy individuals possess circulating antibodies against their indigenous faecal microflora as well as against allogenous faecal microflora: an immunomorphometrical study.

Authors:  H Z Apperloo-Renkema; T G Jagt; R H Tonk; D van der Waaij
Journal:  Epidemiol Infect       Date:  1993-10       Impact factor: 2.451

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Journal:  Mamm Genome       Date:  2009-07-21       Impact factor: 2.957

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