Literature DB >> 6684108

Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B.

N Serizawa, S Serizawa, K Nakagawa, K Furuya, T Okazaki, A Terahara.   

Abstract

Various microorganisms were tested for capability to hydroxylate of ML-236B at the 3 beta-position. As the result, it was found that this ability was limited to a small group of microorganisms, mainly Zygomycetes in fungi, and Nocardia in actinomycetes.

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Year:  1983        PMID： 6684108     DOI： 10.7164/antibiotics.36.887

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  7 in total

1.  Screening of compactin-resistant microorganisms capable of converting compactin to pravastatin.

Authors:  Chao-Hsien Chen; Hui-Yu Hu; Yen-Ching Cho; Wen-Hwei Hsu
Journal:  Curr Microbiol       Date:  2006-06-26       Impact factor: 2.188

2.  Development of a transformation system for the filamentous, ML-236B (compactin)--producing fungus Penicillium citrinum.

Authors:  F Nara; I Watanabe; N Serizawa
Journal:  Curr Genet       Date:  1993-01       Impact factor: 3.886

3.  Identification and characterization of Penicillium citrinum VeA and LaeA as global regulators for ML-236B production.

Authors:  Satoshi Baba; Hiroshi Kinoshita; Takuya Nihira
Journal:  Curr Genet       Date:  2011-12-24       Impact factor: 3.886

Review 4.  A fungal family of transcriptional regulators: the zinc cluster proteins.

Authors:  Sarah MacPherson; Marc Larochelle; Bernard Turcotte
Journal:  Microbiol Mol Biol Rev       Date:  2006-09       Impact factor: 11.056

5.  Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.

Authors:  Kirsty J McLean; Marcus Hans; Ben Meijrink; Wibo B van Scheppingen; Aad Vollebregt; Kang Lan Tee; Jan-Metske van der Laan; David Leys; Andrew W Munro; Marco A van den Berg
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-17       Impact factor: 11.205

6.  Tissue-selective inhibition of sterol synthesis in mice by pravastatin sodium after a single or repeated oral administrations.

Authors:  T Koga; T Kikuchi; A Miyazaki; H Koike
Journal:  Lipids       Date:  1995-08       Impact factor: 1.880

7.  Fermentative production and optimization of mevastatin in submerged fermentation using Aspergillus terreus.

Authors:  Mahin Basha Syed; M Rajasimman
Journal:  Biotechnol Rep (Amst)       Date:  2015-04-09
  7 in total

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