| Literature DB >> 6683750 |
T Arbizu, J Santamaría, J M Gomez, A Quílez, J P Serra.
Abstract
A family with adult spinal and bulbar muscular atrophy with X-linked recessive inheritance (Kennedy's disease) is described. Affected members presented at age 20 with muscle cramps followed insidiously by gynaecomastia, partial loss of secondary sexual traits, loss of libido and inability to maintain an erection. Three had also testicular atrophy and severe oligospermia was found in two patients. Testicular biopsy in one case showed germinal failure with almost normal Leydig cells. Hormonal tests were suggestive of a primary testicular failure. Etiologic possibilities are considered.Entities:
Mesh：
Year: 1983 PMID： 6683750 DOI： 10.1016/0022-510x(83)90022-9
Source DB: PubMed Journal: J Neurol Sci ISSN： 0022-510X Impact factor: 3.181