Literature DB >> 6683661

Neural pathogenesis of experimental scrapie after intraocular inoculation of hamsters.

N Buyukmihci, F Goehring-Harmon, R F Marsh.   

Abstract

Hamsters were inoculated intravitreally with the scrapie agent. All animals developed scrapie and retinal degeneration typical of scrapie. The retinal degeneration was greater in the inoculated eyes than in the uninoculated eyes. Replication of the scrapie agent was rapid in the inoculated eye. Infectivity then spread slowly down the ipsilateral optic nerve to the brain. The replication in the brain paralleled that in the retina of the uninoculated eye. The results support a neural spread of scrapie.

Entities:  

Mesh：

Year:  1983        PMID： 6683661     DOI： 10.1016/0014-4886(83)90271-6

Source DB:  PubMed          Journal:  Exp Neurol        ISSN： 0014-4886            Impact factor:   5.330


  11 in total

Review 1.  Neurodegenerative diseases: expanding the prion concept.

Authors:  Lary C Walker; Mathias Jucker
Journal:  Annu Rev Neurosci       Date:  2015-03-30       Impact factor: 12.449

Review 2.  Corruption and spread of pathogenic proteins in neurodegenerative diseases.

Authors:  Lary C Walker; Harry LeVine
Journal:  J Biol Chem       Date:  2012-08-09       Impact factor: 5.157

Review 3.  The Prion-Like Properties of Amyloid-β Assemblies: Implications for Alzheimer's Disease.

Authors:  Lary C Walker; Juliane Schelle; Mathias Jucker
Journal:  Cold Spring Harb Perspect Med       Date:  2016-07-01       Impact factor: 6.915

4.  Retrograde transport of transmissible mink encephalopathy within descending motor tracts.

Authors:  Jason C Bartz; Anthony E Kincaid; Richard A Bessen
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

5.  Transport of cargo from periphery to brain by circulating monocytes.

Authors:  Amarallys F Cintron; Nirjari V Dalal; Jeromy Dooyema; Ranjita Betarbet; Lary C Walker
Journal:  Brain Res       Date:  2015-07-10       Impact factor: 3.252

6.  Evidence of mitochondrial involvement in scrapie infection.

Authors:  J M Aiken; J L Williamson; R F Marsh
Journal:  J Virol       Date:  1989-04       Impact factor: 5.103

7.  Role of the lymphoreticular system in prion neuroinvasion from the oral and nasal mucosa.

Authors:  Richard A Bessen; Scott Martinka; Jessica Kelly; Daniel Gonzalez
Journal:  J Virol       Date:  2009-04-15       Impact factor: 5.103

Review 8.  Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies.

Authors:  Juan Carlos Polanco; Chuanzhou Li; Liviu-Gabriel Bodea; Ramon Martinez-Marmol; Frederic A Meunier; Jürgen Götz
Journal:  Nat Rev Neurol       Date:  2017-12-15       Impact factor: 42.937

9.  Aβ seeds and prions: How close the fit?

Authors:  Jay Rasmussen; Mathias Jucker; Lary C Walker
Journal:  Prion       Date:  2017-06-28       Impact factor: 3.931

10.  Biophysical characteristics of lipid-induced Aβ oligomers correlate to distinctive phenotypes in transgenic mice.

Authors:  Jhinuk Saha; Dexter N Dean; Shailendra Dhakal; Kelli A Stockmal; Sarah E Morgan; Kristy D Dillon; Munir F Adamo; Yona Levites; Vijayaraghavan Rangachari
Journal:  FASEB J       Date:  2021-02       Impact factor: 5.834
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.