Literature DB >> 6683578

Clinical effect of intravenous immunoglobulin on chronic idiopathic thrombocytopenic purpura.

T Abe, J Matsuda, K Kawasugi, Y Yoshimura, T Kinoshita, M Kazama.   

Abstract

High dose immunoglobulin infusions showed a marked effect on platelet counts in eight out of nine chronic ITP patients and in one SLE patient. In the comparison of different IgG-preparations, the pepsin treated IgG F (ab')2 showed no platelet elevation while the sulfonated did. The elevated platelet count could not be maintained after discontinuation of IgG infusions, but in six out of ten patients the platelet level remained above the pretreatment values. This new treatment seems to be safe and effective in adulthood ITP.

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Year:  1983        PMID: 6683578     DOI: 10.1007/bf02482640

Source DB:  PubMed          Journal:  Blut        ISSN: 0006-5242


  16 in total

Review 1.  Platelet antibody in autoimmune thrombocytopenia.

Authors:  R H Dixon; W F Rosse
Journal:  Br J Haematol       Date:  1975-10       Impact factor: 6.998

2.  In vitro detection of platelet antibody in patients with idiopathic thrombocytopenic purpura and systemic lupus erythematosus.

Authors:  S Karpatkin; G W Siskind
Journal:  Blood       Date:  1969-06       Impact factor: 22.113

3.  Similarities between known antiplatelet antibodies and the factor responsible for thrombocytopenia in idiopathic purpura. Physiologic, serologic and isotopic studies.

Authors:  N R Shulman; V J Marder; R S Weinrach
Journal:  Ann N Y Acad Sci       Date:  1965-06-30       Impact factor: 5.691

Review 4.  Autoimmune thrombocytopenic purpura.

Authors:  S Karpatkin
Journal:  Blood       Date:  1980-09       Impact factor: 22.113

5.  High-dose intravenous gammaglobulin for idiopathic thrombocytopenic purpura.

Authors:  R E Schmidt; U Budde; G Schäfer; I Stroehmann
Journal:  Lancet       Date:  1981-08-29       Impact factor: 79.321

6.  Transient reversal of thrombocytopenia in idiopathic thrombocytopenic purpura by high-dose intravenous gamma globulin.

Authors:  J Fehr; V Hofmann; U Kappeler
Journal:  N Engl J Med       Date:  1982-05-27       Impact factor: 91.245

Review 7.  Chronic idiopathic thrombocytopenic purpura.

Authors:  R McMillan
Journal:  N Engl J Med       Date:  1981-05-07       Impact factor: 91.245

8.  Platelet antibodies in thrombocytopenic patients.

Authors:  U M Hegde; E C Gordon-Smith; S Worlledge
Journal:  Br J Haematol       Date:  1977-01       Impact factor: 6.998

9.  High-dose intravenous IgG in adults with autoimmune thrombocytopenia.

Authors:  A C Newland; J G Treleaven; R M Minchinton; A H Waters
Journal:  Lancet       Date:  1983-01-15       Impact factor: 79.321

10.  Stimulation of lymphocytes by platelet-antibody-complexes and their role in the pathogenesis of idiopathic thrombocytopenia.

Authors:  R Waldschmidt; C Mueller-Eckhardt
Journal:  Blut       Date:  1979-07
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  6 in total

1.  High dose gammaglobulin therapy in adults with idiopathic thrombocytopenic purpura (ITP). Clinical effects.

Authors:  R E Schmidt; U Budde; C Bröschen-Zywietz; G Schäfer; C Mueller-Eckhardt
Journal:  Blut       Date:  1984-01

2.  Intravenous immunoglobulin therapy: new aspects and outlook.

Authors:  P Imbach; S Barandun; C Baumgartner; G Gaedicke; A Hirt; H P Wagner
Journal:  Blut       Date:  1984-06

3.  Specific and nonspecific mechanisms of action of immunoglobulin G in therapy of idiopathic thrombocytopenic purpura (ITP).

Authors:  T W Jungi; P Imbach; S Barandun
Journal:  Blut       Date:  1984-06

4.  Long-term outcomes of laparoscopic versus open splenectomy for immune thrombocytopenia.

Authors:  Kazuhiro Tada; Masayuki Ohta; Kunihiro Saga; Hiroomi Takayama; Teijiro Hirashita; Yuichi Endo; Hiroki Uchida; Yukio Iwashita; Masafumi Inomata
Journal:  Surg Today       Date:  2017-07-19       Impact factor: 2.549

5.  Prediction of the effect of immunoglobulin therapy in ITP.

Authors:  K Kawasugi; J Matsuda; T Abe
Journal:  Blut       Date:  1989-07

6.  The place of intravenous immunoglobulin (IgG i.v.) therapy in thrombocytopenia.

Authors:  G Gaedicke; P Imbach; E Kleihauer
Journal:  Blut       Date:  1984-06
  6 in total

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