Literature DB >> 6683427

Fetal brain transplant: reduction of cognitive deficits in rats with frontal cortex lesions.

R Labbe, A Firl, E J Mufson, D G Stein.   

Abstract

Frontal cortex and cerebellar tissue from fetal rats was implanted into the damaged frontal cortex of adults. Cognitive deficits in spatial alternation learning that follow bilateral destruction of medial frontal cortex were reduced in rats with frontal cortex implants but not in those with implants of cerebellum. Histological evaluation showed that connections were made between the frontal cortex implants and host brain tissue.

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Year:  1983        PMID： 6683427     DOI： 10.1126/science.6683427

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Hippocampal tissue transplants reverse lesion-induced spatial memory deficits in zebra finches (Taeniopygia guttata).

Authors:  S N Patel; N S Clayton; J R Krebs
Journal:  J Neurosci       Date:  1997-05-15       Impact factor: 6.167

2.  Intrastriatal transplantation of cross-species fetal striatal cells reduces abnormal movements in a primate model of Huntington disease.

Authors:  P Hantraye; D Riche; M Maziere; O Isacson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

3.  Analysis of the canine brain transcriptome with an emphasis on the hypothalamus and cerebral cortex.

Authors:  Meenakshi Roy; Namshin Kim; Kyung Kim; Won-Hyong Chung; Rujira Achawanantakun; Yanni Sun; Robert Wayne
Journal:  Mamm Genome       Date:  2013-11-08       Impact factor: 2.957

4.  Cell Therapy From Bench to Bedside Translation in CNS Neurorestoratology Era.

Authors:  Hongyun Huang; Lin Chen; Paul Sanberg
Journal:  Cell Med       Date:  2010-01-01

5.  Implantation of neuronal suspensions into contusive injury sites in the adult rat spinal cord.

Authors:  D W Hoovler; J R Wrathall
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

6.  Fetal cortical transplants in the cerebral hemisphere of newborn rats: a retrograde fluorescent analysis of connections.

Authors:  A J Castro; N Tønder; N A Sunde; J Zimmer
Journal:  Exp Brain Res       Date:  1987       Impact factor: 1.972

7.  Homotopic transplantation of embryonal neocortex tissue into damaged brains of adult rats.

Authors:  G P Obukhova; V V Senatorov; G A Vartanyan
Journal:  Neurosci Behav Physiol       Date:  1989 Jul-Aug

Review 8.  Neural cell adhesion molecule (NCAM) as a quantitative marker in synaptic remodeling.

Authors:  O S Jørgensen
Journal:  Neurochem Res       Date:  1995-05       Impact factor: 3.996

9.  The survival of brain transplants is enhanced by extracts from injured brain.

Authors:  M Nieto-Sampedro; S R Whittemore; D L Needels; J Larson; C W Cotman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205

10.  Transmitter expression and morphological development of embryonic medullary and mesencephalic raphé neurones after transplantation to the adult rat central nervous system. III. Grafts to the striatum.

Authors:  G A Foster; M Schultzberg; F H Gage; A Björklund; T Hökfelt; A C Cuello; A A Verhofstad; T J Visser; P C Emson
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972
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