Literature DB >> 6682797

Polyamine starvation causes parallel increase in nuclear and chromosomal aberrations in a polyamine-dependent strain of CHO.

S Knuutila, P Pohjanpelto.   

Abstract

Deprivation of polyamines and ornithine causes in a polyamine-dependent CHO strain aneuploidy and alterations in nuclear morphology including micronuclei, macronuclei, framented and bulged nuclei. There is also formation of multinucleate cells. The number of micronuclei and certain other nuclear aberrations increase concomitantly with chromosome abberrations.

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Year:  1983        PMID： 6682797     DOI： 10.1016/s0014-4827(83)80024-x

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN： 0014-4827            Impact factor:   3.905


  6 in total

Review 1.  Recent advances in the biochemistry of polyamines in eukaryotes.

Authors:  A E Pegg
Journal:  Biochem J       Date:  1986-03-01       Impact factor: 3.857

Review 2.  Polyamine--DNA nexus: structural ramifications and biological implications.

Authors:  D Balasundaram; A K Tyagi
Journal:  Mol Cell Biochem       Date:  1991-02-02       Impact factor: 3.396

3.  Polyamine starvation prolongs the S and G2 phases of polyamine-dependent (arginase-deficient) CHO cells.

Authors:  S Anehus; P Pohjanpelto; B Baldetorp; E Långström; O Heby
Journal:  Mol Cell Biol       Date:  1984-05       Impact factor: 4.272

4.  Effects of a putrescine analog on Giardia lamblia.

Authors:  C Maia; A Lanfredi-Rangel; K G Santana-Anjos; M F Oliveira; W De Souza; M A Vannier-Santos
Journal:  Parasitol Res       Date:  2008-04-24       Impact factor: 2.289

5.  Mutant strain of Chinese hamster ovary cells with no detectable ornithine decarboxylase activity.

Authors:  P Pohjanpelto; E Hölttä; O A Jänne
Journal:  Mol Cell Biol       Date:  1985-06       Impact factor: 4.272

6.  A new model for disruption of the ornithine decarboxylase gene, SPE1, in Saccharomyces cerevisiae exhibits growth arrest and genetic instability at the MAT locus.

Authors:  B Schwartz; A Hittelman; L Daneshvar; H S Basu; L J Marton; B G Feuerstein
Journal:  Biochem J       Date:  1995-11-15       Impact factor: 3.857
  6 in total

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