Literature DB >> 6682405

Loss of surface fibronectin from human lung fibroblasts exposed to cytotoxin from Clostridium difficile.

T Ahlgren, I Florin, C Jarstrand, M Thelestam.   

Abstract

Clostridium difficile cytotoxin caused an irreversible dose- and time-dependent loss of fibronectin from the surfaces of human lung fibroblasts, paralleling the appearance of the cytopathic effect. Fibronectin was not required for the intoxication process. The results lend further support to a transmembrane connective link between fibronectin and the microfilaments.

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Year:  1983        PMID： 6682405      PMCID： PMC348117          DOI： 10.1128/iai.39.3.1470-1472.1983

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  24 in total

Review 1.  Fibronectins--adhesive glycoproteins of cell surface and blood.

Authors:  K M Yamada; K Olden
Journal:  Nature       Date:  1978-09-21       Impact factor: 49.962

2.  Cytochalasin B releases a major surface-associated glycoprotein, fibronectin, from cultured fibroblasts.

Authors:  M Kurkinen; J Wartiovaara; A Vaheri
Journal:  Exp Cell Res       Date:  1978-01       Impact factor: 3.905

3.  Identification of Clostridium difficile as a cause of pseudomembranous colitis.

Authors:  R H George; J M Symonds; F Dimock; J D Brown; Y Arabi; N Shinagawa; M R Keighley; J Alexander-Williams; D W Burdon
Journal:  Br Med J       Date:  1978-03-18

4.  Thrombin stimulates the production and release of a major surface-associated glycoprotein (fibronectin) in cultures of human fibroblasts.

Authors:  D F Mosher; A Vaheri
Journal:  Exp Cell Res       Date:  1978-03-15       Impact factor: 3.905

5.  Synthesis, secretion, and attachment of LETS glycoprotein in normal and transformed cells.

Authors:  R O Hynes; A T Destree; V M Mautner; I U Ali
Journal:  J Supramol Struct       Date:  1977

6.  Effects of cytochalasin B and colchicine on attachment of a major surface protein of fibroblasts.

Authors:  I U Ali; R O Hynes
Journal:  Biochim Biophys Acta       Date:  1977-11-15

7.  Clindamycin-induced enterocolitis in hamsters as a model of pseudomembranous colitis in patients.

Authors:  T W Chang; J G Bartlett; S L Gorbach; A B Onderdonk
Journal:  Infect Immun       Date:  1978-05       Impact factor: 3.441

8.  Clostridium difficile and antibiotic associated diarrhoea in Sweden.

Authors:  B Aronsson; R Möllby; C E Nord
Journal:  Scand J Infect Dis Suppl       Date:  1982

9.  Clostridium difficile and the aetiology of pseudomembranous colitis.

Authors:  H E Larson; A B Price; P Honour; S P Borriello
Journal:  Lancet       Date:  1978-05-20       Impact factor: 79.321

10.  Action of cytochalasin D on cells of established lines. II. Cortex and microfilaments.

Authors:  A F Miranda; G C Godman; S W Tanenbaum
Journal:  J Cell Biol       Date:  1974-08       Impact factor: 10.539
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  4 in total

Review 1.  Clostridium difficile: its disease and toxins.

Authors:  D M Lyerly; H C Krivan; T D Wilkins
Journal:  Clin Microbiol Rev       Date:  1988-01       Impact factor: 26.132

2.  Identification of a novel virulence factor in Clostridium difficile that modulates toxin sensitivity of cultured epithelial cells.

Authors:  Masashi Miura; Haru Kato; Osamu Matsushita
Journal:  Infect Immun       Date:  2011-07-11       Impact factor: 3.441

3.  Factors influencing the phagocytosis of Clostridium difficile by human polymorphonuclear leukocytes.

Authors:  D C Dailey; A Kaiser; R H Schloemer
Journal:  Infect Immun       Date:  1987-07       Impact factor: 3.441

4.  Differential cytotoxic effects of toxins A and B isolated from Clostridium difficile.

Authors:  S W Rothman; J E Brown; A Diecidue; D A Foret
Journal:  Infect Immun       Date:  1984-11       Impact factor: 3.441
  4 in total

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