Literature DB >> 6681604

Influence of cis-platinum on healing of enterostomies in the rat.

U Engelmann, K Grimm, J Grönniger, R Bürger, G H Jacobi.   

Abstract

The influence of cis-platinum on the wound healing of bowel anastomoses was studied in 104 male Sprague-Dawley rats. After a single preoperative doses of 5 mg/kg body weight, the wound-breaking strength (WBS) was tested with a material tester on the 4th, 7th, 14th and 28th day postoperatively. The WBS was significantly lower in treated animals as compared to the untreated controls. The reasons for this are discussed in comparison with other cytotoxic agents. Before cis-platinum can be used as adjuvant chemotherapy to cystectomy, which is frequently combined with an ileum or colon conduit procedure, further investigations on the operative side effects of cis-platinum on bowel anastomoses are necessary.

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Year:  1983        PMID： 6681604     DOI： 10.1159/000474042

Source DB:  PubMed          Journal:  Eur Urol        ISSN： 0302-2838            Impact factor:   20.096


  5 in total

1.  Histologic evaluation of wound healing in experimental intestinal anastomoses: effects of antineoplastic agents.

Authors:  D B de Roy van Zuidewijn; P H Schillings; T Wobbes; H H de Boer
Journal:  Int J Exp Pathol       Date:  1992-08       Impact factor: 1.925

Review 2.  Harnessing cancer immunotherapy during the unexploited immediate perioperative period.

Authors:  Pini Matzner; Elad Sandbank; Elad Neeman; Oded Zmora; Vijaya Gottumukkala; Shamgar Ben-Eliyahu
Journal:  Nat Rev Clin Oncol       Date:  2020-02-17       Impact factor: 66.675

3.  Wound healing in patients with cancer.

Authors:  Wyatt G Payne; Deepak K Naidu; Chad K Wheeler; David Barkoe; Marni Mentis; R Emerick Salas; David J Smith; Martin C Robson
Journal:  Eplasty       Date:  2008-01-11

4.  Inhibition of basal and TGF beta-induced fibroblast collagen synthesis by antineoplastic agents. Implications for wound healing.

Authors:  T Hendricks; M F Martens; C M Huyben; T Wobbes
Journal:  Br J Cancer       Date:  1993-03       Impact factor: 7.640

5.  Comparison of postoperative complications in advanced head and neck cancer patients receiving neoadjuvant chemotherapy followed by surgery versus surgery alone.

Authors:  Poonam Joshi; Amit Joshi; Kumar Prabhash; Vanita Noronha; Pankaj Chaturvedi
Journal:  Indian J Med Paediatr Oncol       Date:  2015 Oct-Dec
  5 in total

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