Literature DB >> 6677539

Thousand litre scale microcarrier culture of Vero cells for killed polio virus vaccine. Promising results.

B Montagnon, J C Vincent-Falquet, B Fanget.   

Abstract

Through the progress of scientific knowledge the Vero cell line was considered to be a suitable alternative cell substrate for the industrial production of Polio Virus. Using microcarrier culture, more than 10(12) cells could be obtained weekly for virus inoculation. The virus yield is around 60 D units/ml for type I; 20 D units/ml for type II, and 50 D units/ml for type III.

Mesh：

Substances：

Year:  1983        PMID： 6677539

Source DB:  PubMed          Journal:  Dev Biol Stand        ISSN： 0301-5149


  9 in total

1.  Evaluation of the serum-free medium MDSS2 for the production of poliovirus on vero cells in bioreactors.

Authors:  O W Merten; R Wu; E Couvé; R Crainic
Journal:  Cytotechnology       Date:  1997-11       Impact factor: 2.058

2.  A microcarrier-based cell culture process for the production of a bovine respiratory syncytial virus vaccine.

Authors:  E Moran
Journal:  Cytotechnology       Date:  1999-03       Impact factor: 2.058

3.  Introduction to animal cell culture technology-past, present and future.

Authors:  O-W Merten
Journal:  Cytotechnology       Date:  2006-08-03       Impact factor: 2.058

4.  The new medium MDSS2N, free of any animal protein supports cell growth and production of various viruses.

Authors:  O W Merten; H Kallel; J C Manuguerra; M Tardy-Panit; R Crainic; F Delpeyroux; S Van der Werf; P Perrin
Journal:  Cytotechnology       Date:  1999-07       Impact factor: 2.058

5.  Enhanced production of human recombinant proteins from CHO cells grown to high densities in macroporous microcarriers.

Authors:  T Tharmalingam; K Sunley; M Spearman; M Butler
Journal:  Mol Biotechnol       Date:  2011-11       Impact factor: 2.695

Review 6.  Advances in cell culture: anchorage dependence.

Authors:  Otto-Wilhelm Merten
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-02-05       Impact factor: 6.237

7.  Evaluation of the new serum-free medium (MDSS2) for the production of different biologicals: use of various cell lines.

Authors:  O W Merten; J V Kierulff; N Castignolles; P Perrin
Journal:  Cytotechnology       Date:  1994       Impact factor: 2.058

8.  Kinetics and metabolic specificities of Vero cells in bioreactor cultures with serum-free medium.

Authors:  Sébastien Quesney; Annie Marc; Catherine Gerdil; Cyrille Gimenez; Jacqueline Marvel; Yves Richard; Bernard Meignier
Journal:  Cytotechnology       Date:  2003-05       Impact factor: 2.058

9.  Characterization of Vero cell growth and death in bioreactor with serum-containing and serum-free media.

Authors:  S Quesney; J Marvel; A Marc; C Gerdil; B Meignier
Journal:  Cytotechnology       Date:  2001-03       Impact factor: 2.058
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.