Literature DB >> 66770

HLA determinants in chronic active liver disease: possible relation of HLA-Dw3 to prognosis.

G Opelz, A J Vogten, W H Summerskill, S W Schalm, P I Terasaki.   

Abstract

Thirty-eight patients with severe chronic active liver disease (CALD) were found to have a significantly higher frequency of HLA-Dw3 (68%) than 91 healthy controls (24%) (P less than 0;0001). The association of CALD was statistically significantly stronger with the D locus than with the B locus of HLA. The response to treatment was significantly worse in patients with HLA-Dw3 than in patients who lacked this antigen.

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Year:  1977        PMID: 66770     DOI: 10.1111/j.1399-0039.1977.tb01077.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  13 in total

1.  Response to HBV vaccination in patients with severe liver disease. Absence of an HLA effect.

Authors:  D H Van Thiel; J S Gavaler
Journal:  Dig Dis Sci       Date:  1992-09       Impact factor: 3.199

2.  A possible association between basic amino acids of position 13 of DRB1 chains and autoimmune hepatitis.

Authors:  M Ota; T Seki; K Kiyosawa; S Furuta; K Hino; T Kondo; H Fukushima; K Tsuji; H Inoko
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

Review 3.  Immunological aspects of liver disease.

Authors:  A L Eddleston; P T Donaldson; J E Hegarty; B D Reed
Journal:  Gut       Date:  1991-09       Impact factor: 23.059

Review 4.  Autoimmune Hepatitis: Surviving Crises of Doubt and Elimination.

Authors:  Albert J Czaja
Journal:  Clin Liver Dis (Hoboken)       Date:  2020-03-02

Review 5.  Autoimmune hepatitis. Evolving concepts and treatment strategies.

Authors:  A J Czaja
Journal:  Dig Dis Sci       Date:  1995-02       Impact factor: 3.199

Review 6.  Thygeson's superficial punctate keratitis: natural history and association with HLA DR3.

Authors:  R W Darrell
Journal:  Trans Am Ophthalmol Soc       Date:  1981

Review 7.  Genetic determinants of autoimmune chronic active hepatitis.

Authors:  I R Mackay; S Whittingham; J D Mathews; B D Tait
Journal:  Springer Semin Immunopathol       Date:  1980-12

8.  Interaction of HLA and Gm in autoimmune chronic active hepatitis.

Authors:  S Whittingham; J D Mathews; M S Schanfield; B D Tait; I R Mackay
Journal:  Clin Exp Immunol       Date:  1981-01       Impact factor: 4.330

9.  Lack of association between HLA antigen DR3 and alpha 1-antitrypsin deficiency in liver transplant recipients.

Authors:  A Casavilla; R Gordon; D H van Thiel; T E Starzl
Journal:  Dig Dis Sci       Date:  1993-08       Impact factor: 3.199

10.  Simultaneous occurrence of primary sclerosing cholangitis and autoimmune chronic active hepatitis in a patient with ulcerative colitis.

Authors:  M Rabinovitz; A J Demetris; C F Bou-Abboud; D H Van Thiel
Journal:  Dig Dis Sci       Date:  1992-10       Impact factor: 3.199

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