Literature DB >> 6671226

Species differences in metabolism of sodium 2-[4-(2-oxocyclopentylmethyl)-phenyl]propionate dihydrate (loxoprofen sodium), a new anti-inflammatory agent.

Y Tanaka, Y Nishikawa, R Hayashi.   

Abstract

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Year:  1983        PMID： 6671226     DOI： 10.1248/cpb.31.3656

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


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  4 in total

1.  CBR1 rs9024 genotype status impacts the bioactivation of loxoprofen in human liver.

Authors:  Adolfo Quiñones-Lombraña; Nasi Li; Virginia Del Solar; G Ekin Atilla-Gokcumen; Javier G Blanco
Journal:  Biopharm Drug Dispos       Date:  2018-06       Impact factor: 1.627

2.  Efficacy and safety of loxoprofen hydrogel patch versus loxoprofen tablet in patients with knee osteoarthritis: a randomized controlled non-inferiority trial.

Authors:  Rong Mu; Chun-de Bao; Zhi-wei Chen; Yi Zheng; Guo-chun Wang; Dong-bao Zhao; Shao-xian Hu; Yu-jun Li; Zeng-wu Shao; Zhi-yi Zhang; Wei-guo Xiao; Weiya Zhang; Zhan-guo Li
Journal:  Clin Rheumatol       Date:  2014-06-14       Impact factor: 2.980

3.  Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation.

Authors:  Riya Shrestha; Pil Joung Cho; Sanjita Paudel; Aarajana Shrestha; Mi Jeong Kang; Tae Cheon Jeong; Eung-Seok Lee; Sangkyu Lee
Journal:  Pharmaceutics       Date:  2018-08-02       Impact factor: 6.321

4.  Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators.

Authors:  Sanjita Paudel; Aarajana Shrestha; Piljoung Cho; Riya Shrestha; Younah Kim; Taeho Lee; Ju-Hyun Kim; Tae Cheon Jeong; Eung-Seok Lee; Sangkyu Lee
Journal:  Pharmaceutics       Date:  2019-09-16       Impact factor: 6.321
  4 in total

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