Exocrine function of the pancreas in regularly swimming rats.

The exocrine function of the pancreas was investigated in the course of adaptation to regular physical activity. In albino rats exercized by swimming for six weeks it has been observed that - in response to an identical physiological stimulation (liquid food via gastric tube) and under ad libitum feeding the rate of secretion and enzyme activity exceeded control values by 100 to 150%; - in pair-fed rats the values of the exercized animals were 50 to 70% higher, and - vagotomy suspended this effect even when food was offered ad libitum. On the basis of these results adaptation to regular exercise involves the exocrine function of the pancreas. In this functional increase both the increased food intake after training sessions and the direct effect of muscular work have a share. For adaptation an intact innervation is necessary.