Literature DB >> 6670502

Early effects of parathormone and calcitonin on the number of osteoclasts and on serum-calcium in rats.

T Hedlund, A Hulth, O Johnell.   

Abstract

Using succinic dehydrogenase staining of osteoclasts, the authors have studied the early effects on these cells of parathormone and calcitonin in rats. Thirty minutes after injection of the hormones the number of osteoclasts had increased (parathormone) or decreased (calcitonin), associated with inverse changes in total serum-calcium. The results confirm earlier studies showing the remarkably rapid changes in the number of osteoclasts after substances acting on serum calcium.

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Year:  1983        PMID： 6670502     DOI： 10.3109/17453678308992912

Source DB:  PubMed          Journal:  Acta Orthop Scand        ISSN： 0001-6470


  12 in total

Review 1.  Intranasal salcatonin (salmon calcitonin). A review of its pharmacological properties and role in the management of postmenopausal osteoporosis.

Authors:  G L Plosker; D McTavish
Journal:  Drugs Aging       Date:  1996-05       Impact factor: 3.923

2.  The effect of high-dose salmon calcitonin on bone mineral metabolism in the normal rat.

Authors:  N Glajchen; S Thomas; P Jowell; S Epstein; F Ismail; M Fallon
Journal:  Calcif Tissue Int       Date:  1990-01       Impact factor: 4.333

3.  Calcitonin has direct effects on 3[H]-thymidine incorporation and alkaline phosphatase activity in human osteoblast-line cells.

Authors:  J R Farley; J E Wergedal; S L Hall; S Herring; N M Tarbaux
Journal:  Calcif Tissue Int       Date:  1991-05       Impact factor: 4.333

4.  Calcitonin acutely increases tyrosyl-phosphorylation of proteins in human osteosarcoma (SaOS-2) cells.

Authors:  A Thomas; S L Hall; V Nicolas; K H Lau; J R Farley
Journal:  Calcif Tissue Int       Date:  1995-04       Impact factor: 4.333

5.  Effect of intranasal salmon calcitonin therapy on bone mass and bone turnover in early postmenopausal women: a dose-response study.

Authors:  K Overgaard
Journal:  Calcif Tissue Int       Date:  1994-08       Impact factor: 4.333

6.  Calcitonin (but not calcitonin gene-related peptide) increases mouse bone cell proliferation in a dose-dependent manner, and increases mouse bone formation, alone and in combination with fluoride.

Authors:  J R Farley; S L Hall; N M Tarbaux
Journal:  Calcif Tissue Int       Date:  1989-10       Impact factor: 4.333

7.  Long-term treatment of established osteoporosis with intranasal calcitonin.

Authors:  K Overgaard; C Christiansen
Journal:  Calcif Tissue Int       Date:  1991       Impact factor: 4.333

8.  Effect of salcatonin given intranasally on bone mass and fracture rates in established osteoporosis: a dose-response study.

Authors:  K Overgaard; M A Hansen; S B Jensen; C Christiansen
Journal:  BMJ       Date:  1992-09-05

9.  Inhibitory effect of salmon calcitonin on bone resorption: morphological study of the tibial growth plate in rats.

Authors:  U E Pazzaglia; G Zatti; A Di Nucci; A Coci
Journal:  Calcif Tissue Int       Date:  1993-02       Impact factor: 4.333

10.  Two biochemical indices of mouse bone formation are increased, in vivo, in response to calcitonin.

Authors:  J R Farley; S L Hall; S Herring; N M Tarbaux
Journal:  Calcif Tissue Int       Date:  1992-01       Impact factor: 4.333
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