| Literature DB >> 6669169 |
A R Waldorf, C Halde, N A Vedros.
Abstract
Antibody raised in mice against mycelial homogenates of Rhizomucor pusillus was effective in passive immunization against pulmonary and disseminated mucormycosis (phycomycosis) in immunocompromised mice. Mice intranasally inoculated and infected with Rh. pusillus and treated with antisera had a statistically significant increased resistance to infection and a diminished secondary dissemination of viable fungal fragments. Histological examination of infected lung tissues showed that antibody treated animals were apparently able to degrade hyphal fragments.Entities:
Mesh:
Year: 1983 PMID: 6669169 DOI: 10.1007/bf00437021
Source DB: PubMed Journal: Mycopathologia ISSN: 0301-486X Impact factor: 2.574