Literature DB >> 6667830

Transforming activity of human melanoma DNA.

T Sekiya, S Hirohashi, S Nishimura, T Sugimura.   

Abstract

Cellular DNA transfection to mouse NIH3T3 cells revealed transforming activity of human malignant melanoma DNA. The corresponding human sequence was cloned from the transformed mouse cells. By hybridization to viral oncogenes, the transforming gene in human melanoma was identified as a homologue of viral Ha-ras gene.

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Year:  1983        PMID： 6667830

Source DB:  PubMed          Journal:  Gan        ISSN： 0016-450X


  4 in total

Review 1.  Human cancer and cellular oncogenes.

Authors:  S Nishimura; T Sekiya
Journal:  Biochem J       Date:  1987-04-15       Impact factor: 3.857

2.  A simple method for detecting single base substitutions and its application to HLA-DPB1 typing.

Authors:  T Oka; H Matsunaga; K Tokunaga; S Mitsunaga; T Juji; A Yamane
Journal:  Nucleic Acids Res       Date:  1994-05-11       Impact factor: 16.971

3.  Molecular cloning and the total nucleotide sequence of the human c-Ha-ras-1 gene activated in a melanoma from a Japanese patient.

Authors:  T Sekiya; M Fushimi; H Hori; S Hirohashi; S Nishimura; T Sugimura
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

4.  A novel combination of K-ras and myc amplification accompanied by point mutational activation of K-ras in a human lung cancer.

Authors:  Y Taya; K Hosogai; S Hirohashi; Y Shimosato; R Tsuchiya; N Tsuchida; M Fushimi; T Sekiya; S Nishimura
Journal:  EMBO J       Date:  1984-12-01       Impact factor: 11.598
  4 in total

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