Literature DB >> 6667267

Specific G1-S phase cell cycle block by beryllium as demonstrated by cytofluorometric analysis.

D N Skilleter, R J Price, R F Legg.   

Abstract

Inhibition of cell division by beryllium (Be2+) has been examined in synchronized cultures of a liver-derived cell line (BL9L cells) using cytofluorometric cell cycle analysis. Results show that a selective dose-related block of the G1-pre-S transition is produced, with other periods of the cell cycle appearing relatively insensitive.

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Year:  1983        PMID： 6667267      PMCID： PMC1152575          DOI： 10.1042/bj2160773

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  17 in total

1.  A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples.

Authors:  M A Markwell; S M Haas; L L Bieber; N E Tolbert
Journal:  Anal Biochem       Date:  1978-06-15       Impact factor: 3.365

Review 2.  Nuclear proteins and the cell cycle.

Authors:  G Stein; R Baserga
Journal:  Adv Cancer Res       Date:  1972       Impact factor: 6.242

3.  Development of resistance to cytotoxicity during aflatoxin carcinogenesis.

Authors:  D J Judah; R F Legg; G E Neal
Journal:  Nature       Date:  1977-01-27       Impact factor: 49.962

4.  Cell cycle-related changes in nuclear chromatin of stimulated lymphocytes as measured by flow cytometry.

Authors:  Z Darzynkiewicz; F Traganos; T K Sharpless; M R Melamed
Journal:  Cancer Res       Date:  1977-12       Impact factor: 12.701

5.  Phagocytosis of latex particles in relation to the cell cycle in 3T3 cells.

Authors:  P A Riley; R T Dean
Journal:  Exp Cell Biol       Date:  1978

6.  The uptake and subsequent loss of beryllium by rat liver parenchymal and non-parenchymal cells after the intravenous administration of particulate and soluble forms.

Authors:  D N Skilleter; R J Price
Journal:  Chem Biol Interact       Date:  1978-03       Impact factor: 5.192

7.  Binding of beryllium to nuclear acidic proteins.

Authors:  V H Parker; C Stevens
Journal:  Chem Biol Interact       Date:  1979-07       Impact factor: 5.192

8.  Effects of beryllium on deoxyribonucleic acid-synthesizing enzymes in regenerating rat liver.

Authors:  H P Witschi
Journal:  Biochem J       Date:  1970-12       Impact factor: 3.857

9.  Relative toxicities of particulate and soluble forms of beryllium to a rat liver parenchymal cell line in culture and possible mechanisms of uptake.

Authors:  D N Skilleter; A J Paine
Journal:  Chem Biol Interact       Date:  1979-01       Impact factor: 5.192

10.  Endocytosis and chloroquine accumulation during the cell cycle of hepatoma cells in culture.

Authors:  J Quintart; M A Leroy-Houyet; A Trouet; P Baudhuin
Journal:  J Cell Biol       Date:  1979-09       Impact factor: 10.539
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  5 in total

1.  High temperature enhances cytotoxicity of mercury (HgCl2) on HeLa S3 cells.

Authors:  T Kishimoto; Y Fukuzawa; M Tada
Journal:  Int J Biometeorol       Date:  1990-12       Impact factor: 3.787

2.  Stimulatory and cytotoxic effects of beryllium on proliferation of mouse spleen lymphocytes in vitro.

Authors:  R J Price; D N Skilleter
Journal:  Arch Toxicol       Date:  1985-01       Impact factor: 5.153

3.  Fluorescence-activated sorting of rat hepatocytes based on their mixed function oxidase activities towards diethoxyfluorescein.

Authors:  I N White; M L Green; R F Legg
Journal:  Biochem J       Date:  1987-10-01       Impact factor: 3.857

4.  p53-dependent up-regulation of CDKN1A and down-regulation of CCNE2 in response to beryllium.

Authors:  P Gorjala; J G Cairncross; R K Gary
Journal:  Cell Prolif       Date:  2016-09-09       Impact factor: 6.831

5.  A system for transformation of rat liver cells in vitro by acute treatment with aflatoxin.

Authors:  S Sinha; L J Hockin; G E Neal
Journal:  Br J Cancer       Date:  1987-06       Impact factor: 7.640
  5 in total

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