Prognostic criteria in patients with endometrial cancer.

Between 1970 and 1977 216 patients were operated on for adenocarcinoma of the endometrium at the I. Universitäts-Frauenklinik, Munich. The 5-year-survival rate for stage Ia was 79.7%, for stage Ib 86.4%, and for stage II 66.7%. Reliable prognostic criteria were tumor grading, lymphatic invasion, and myometrial tumor invasion. The 5-year-survival rate in patients with grade 1 carcinoma was 88.9% in patients with grade 3 carcinoma only 33.3% Patients with adenoacanthoma had a 5-year-survival rate of 73.3%, those with an adenosquamous carcinoma a 5-year-survival rate of 50%. Patients with no evidence of lymphatic invasion showed a 5-year-survival rate of 84.9%, those with proven invasion of lymphatic vessels a survival rate of 52.9%. In patients with tumor infiltrating one third of the myometrium the 5-year-survival rate was 90%. In patients with tumor infiltrating two thirds of the myometrium the 5-year-survival rate was 66.7%, and with infiltration of the full thickness of myometrium it was 33.3%.