Effects of cross reinnervation on the energetics of rat skeletal muscle.

Experiments were carried out to investigate the changes which occur in the energy production of cross reinnervated fast and slow twitch skeletal muscles. Rat soleus (SOL) and extensor digitorum longus (EDL) muscles were used in myothermic experiments. It was found that the energy production of cross reinnervated skeletal muscle is largely determined by the source of the nervous innervation; as are the dynamic and histological properties of mammalian skeletal muscle. There was an increase in the energy production of crossed soleus muscle and a concomitant reduction in the energy production of crossed EDL. The changes observed correlated well with the measured changes in the force-velocity properties.