Literature DB >> 6663633

Observation of a second phosphate pool in the perfused heart by 31P NMR; is this the mitochondrial phosphate?

P B Garlick, T R Brown, R H Sullivan, K Ugurbil.   

Abstract

We report here our observations on perfused rat hearts using 31P NMR which show that inorganic phosphate (Pi) is located in two regions of differing pH. From the chemical shifts of the Pi signals and their behaviour under various stimuli we identify one signal (pH 7.0) as coming from the cytosol and suggest that the other (pH 7.38) comes from the mitochondrial matrix space.

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Year:  1983        PMID: 6663633     DOI: 10.1016/0022-2828(83)90347-4

Source DB:  PubMed          Journal:  J Mol Cell Cardiol        ISSN: 0022-2828            Impact factor:   5.000


  8 in total

1.  In vivo 31P MRS detection of an alkaline inorganic phosphate pool with short T1 in human resting skeletal muscle.

Authors:  H E Kan; D W J Klomp; C S Wong; V O Boer; A G Webb; P R Luijten; J A Jeneson
Journal:  NMR Biomed       Date:  2010-10       Impact factor: 4.044

2.  Studies on the compartmentation of DOG metabolism in the brain.

Authors:  H S Bachelard; K J Brooks; O Garofalo
Journal:  Neurochem Res       Date:  1991-09       Impact factor: 3.996

Review 3.  Phosphate transport processes in eukaryotic cells.

Authors:  J P Wehrle; P L Pedersen
Journal:  J Membr Biol       Date:  1989-11       Impact factor: 1.843

4.  Bound inorganic phosphate and early contractile failure in global ischaemia.

Authors:  L C Armiger; J P Headrick; L R Jordan; R J Willis
Journal:  Basic Res Cardiol       Date:  1995 Nov-Dec       Impact factor: 17.165

5.  Dual Effect of Phosphate Transport on Mitochondrial Ca2+ Dynamics.

Authors:  An-Chi Wei; Ting Liu; Brian O'Rourke
Journal:  J Biol Chem       Date:  2015-05-11       Impact factor: 5.157

6.  Ischemic changes in myocardial ionic contents of the isolated perfused rat hearts as studied by NMR.

Authors:  T Ishibashi; M Nakazawa; S Imai
Journal:  Mol Cell Biochem       Date:  1993-02-17       Impact factor: 3.396

7.  (31)P-MRS of healthy human brain: ATP synthesis, metabolite concentrations, pH, and T1 relaxation times.

Authors:  Jimin Ren; A Dean Sherry; Craig R Malloy
Journal:  NMR Biomed       Date:  2015-09-24       Impact factor: 4.044

8.  Mitochondrial NAD(P)H In vivo: Identifying Natural Indicators of Oxidative Phosphorylation in the (31)P Magnetic Resonance Spectrum.

Authors:  Kevin E Conley; Amir S Ali; Brandon Flores; Sharon A Jubrias; Eric G Shankland
Journal:  Front Physiol       Date:  2016-03-30       Impact factor: 4.566

  8 in total

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