| Literature DB >> 6661705 |
E E Ishiguro, T Ainsworth, D H Shaw, W W Kay, T J Trust.
Abstract
Cell wall lipopolysaccharide (LPS) was identified as the receptor for the Aeromonas salmonicida bacteriophage strain 55R-1. Mutants of A. salmonicida resistant to phage 55R-1 were unable to adsorb phage 55R-1 and were shown to be defective in LPS structure. Purified A. salmonicida LPS inactivated phage 55R-1, but the O-polysaccharide and the core oligosaccharide portions of the LPS were ineffective. These results suggest that lipid A was required for receptor activity. Antibodies directed against LPS also inhibited phage adsorption.Entities:
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Year: 1983 PMID： 6661705 DOI： 10.1139/m83-223
Source DB: PubMed Journal: Can J Microbiol ISSN： 0008-4166 Impact factor: 2.419