Literature DB >> 6661650

A topographic quantitative method for measuring brain tissue pH under physiological and pathophysiological conditions.

L Csiba, W Paschen, K A Hossmann.   

Abstract

A technique was developed for the quantitative regional assessment of brain pH by a modification of the umbelliferone method. Twenty micron thick sections were brought into contact with umbelliferone-soaked paper strips and the fluorescence (450 nm) following excitation at 370 nm and 340 nm was recorded photographically. The 340 nm excitation image was subtracted from 370 nm picture, using a computerized image-processing system. Regional pH values were measured in rats and cats under normal and ischemic conditions.

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Year:  1983        PMID: 6661650     DOI: 10.1016/0006-8993(83)90037-9

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  21 in total

1.  Insulin protects cognitive function in experimental stroke.

Authors:  A J Strong; J E Fairfield; E Monteiro; M Kirby; A R Hogg; M Snape; L Ross-Field
Journal:  J Neurol Neurosurg Psychiatry       Date:  1990-10       Impact factor: 10.154

2.  Two-stage resuscitation of the cat brain after prolonged cardiac arrest.

Authors:  K Seo; S Ishimaru; K A Hossmann
Journal:  Intensive Care Med       Date:  1991       Impact factor: 17.440

3.  Influence of severe hemodilution on brain function and brain oxidative metabolism in the cat.

Authors:  R Bauer; T Iijima; K A Hossmann
Journal:  Intensive Care Med       Date:  1996-01       Impact factor: 17.440

4.  H+ permeation and pH regulation at a mammalian serotonin transporter.

Authors:  Y Cao; S Mager; H A Lester
Journal:  J Neurosci       Date:  1997-04-01       Impact factor: 6.167

Review 5.  Intracellular pH determination by absorption spectrophotometry of neutral red.

Authors:  J C LaManna
Journal:  Metab Brain Dis       Date:  1987-09       Impact factor: 3.584

6.  Effect of extracorporeal life support on cerebral blood flow, metabolism and electrophysiology in normothermic cats.

Authors:  T Iijima; T Back; K A Hossmann
Journal:  Intensive Care Med       Date:  1995-01       Impact factor: 17.440

7.  Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging.

Authors:  W Mueller-Klieser; S Walenta
Journal:  Histochem J       Date:  1993-06

8.  Experimental transplantation gliomas in the adult cat brain. 3. Regional biochemistry.

Authors:  F Linn; K Seo; K A Hossmann
Journal:  Acta Neurochir (Wien)       Date:  1989       Impact factor: 2.216

9.  Spatial and temporal changes in tissue pH and ATP distribution in a new model of reversible focal forebrain ischemia in the rat.

Authors:  D Bereczki; L Csiba
Journal:  Metab Brain Dis       Date:  1993-09       Impact factor: 3.584

10.  Fluorescent histochemical localization of lipid peroxidation during brain reperfusion following cardiac arrest.

Authors:  B C White; A Daya; D J DeGracia; B J O'Neil; J M Skjaerlund; S Trumble; G S Krause; J A Rafols
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

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