| Literature DB >> 6660863 |
J G Cassey, D A Clark, P Merrick, B Jones.
Abstract
After a single 500-mg intravenous dose of metronidazole, plasma and dialysate levels were measured over a 7.5-h period in five patients undergoing peritoneal dialysis for terminal renal failure. Approximately 10% of this dose was removed by dialysis during that period, and therapeutic levels were maintained in plasma. No routine adjustment in the dosage of metronidazole appears necessary in patients undergoing peritoneal dialysis.Entities:
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Year: 1983 PMID: 6660863 PMCID: PMC185414 DOI: 10.1128/AAC.24.6.950
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191