Literature DB >> 6660862

Establishment of a murine cell line resistant to arabinosyladenine and devoid of adenosine deaminase activity.

C Shipman, S L Tong, S H Smith, N B Katlama, J C Drach.   

Abstract

A population of cells stably resistant to a concentration of arabinosyladenine 100-fold greater than that tolerated by wild-type cells was selected over a period of 15 months. The cells are not cross resistant to arabinosylcytosine and may have at least one kinase with altered substrate specificity.

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Year:  1983        PMID： 6660862      PMCID： PMC185413          DOI： 10.1128/AAC.24.6.947

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  14 in total

1.  Absence of adenosine deaminase activity in a mammalian cell line transformed by Rous sarcoma virus.

Authors:  C Shipman; J C Drach
Journal:  Science       Date:  1978-06-09       Impact factor: 47.728

2.  The biochemical basis for resistance to adenine arabinoside in a mutant of Toxoplasma gondii.

Authors:  E R Pfefferkorn; L C Pfefferkorn
Journal:  J Parasitol       Date:  1978-06       Impact factor: 1.276

3.  Antiviral activity of arabinosyladenine and arabinosylhypoxanthine in herpes simplex virus-infected KB cells: selective inhibition of viral deoxyribonucleic acid synthesis in synchronized suspension cultures.

Authors:  C Shipman; S H Smith; R H Carlson; J C Drach
Journal:  Antimicrob Agents Chemother       Date:  1976-01       Impact factor: 5.191

4.  Selective inhibition of nuclear DNA synthesis by 9- -D-arabinofuranosyl adenine in rat cells transformed by Rous sarcoma virus.

Authors:  C Shipman; S H Smith; J C Drach
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

5.  Isolation and characterization of tunicamycin resistant mutants from Chinese hamster ovary cells.

Authors:  T Sudo; K Onodera
Journal:  J Cell Physiol       Date:  1979-10       Impact factor: 6.384

6.  Antiproliferative effects of 9-beta-d-arabinofuranosyladenine in a mammalian cell line devoid of adenosine deaminase activity.

Authors:  J C Drach; J N Sandberg; C Shipman
Journal:  J Dent Res       Date:  1977-03       Impact factor: 6.116

7.  Resistance to 9-beta-D-arabinofuranosyladenine in murine tumor cells.

Authors:  G A LePage
Journal:  Cancer Res       Date:  1978-08       Impact factor: 12.701

8.  Evaluation of 4-(2-hydroxyethyl)-1-piperazineëthanesulfonic acid (HEPES) as a tissue culture buffer.

Authors:  C Shipman
Journal:  Proc Soc Exp Biol Med       Date:  1969-01

9.  Alteration of ribonucleotide reductase in aphidicolin-resistant mutants of mouse FM3A cells with associated resistance to arabinosyladenine and arabinosylcytosine.

Authors:  D Ayusawa; K Iwata; T Seno
Journal:  Somatic Cell Genet       Date:  1981-01

Review 10.  Vidarabine: a preliminary review of its pharmacological properties and therapeutic use.

Authors:  R Whitley; C Alford; F Hess; R Buchanan
Journal:  Drugs       Date:  1980-10       Impact factor: 9.546
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  1 in total

1.  Broad-spectrum antiviral activities of neplanocin A, 3-deazaneplanocin A, and their 5'-nor derivatives.

Authors:  E De Clercq; M Cools; J Balzarini; V E Marquez; D R Borcherding; R T Borchardt; J C Drach; S Kitaoka; T Konno
Journal:  Antimicrob Agents Chemother       Date:  1989-08       Impact factor: 5.191
  1 in total

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