Literature DB >> 6658004

Effect of indomethacin on aloin and 1,8 dioxianthraquinone-induced production of prostaglandins in rat isolated colon.

F Capasso, N Mascolo, G Autore, M R Duraccio.   

Abstract

The effect of aloin and 1,8 dioxyanthraquinone on the release of prostaglandin-like material (PG) from rat isolated colon has been investigated. Orally administered aloin and 1,8 dioxyanthraquinone stimulates PG production by subsequently isolated segments of colon. Indomethacin was able to prevent this increased production of PG. These results suggest that the laxative properties of aloin and 1,8 dioxyanthraquinone may depend, at least in part, on increased prostaglandin synthesis by the intestinal tissue.

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Year:  1983        PMID： 6658004     DOI： 10.1016/0090-6980(83)90193-4

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  4 in total

1.  The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipation in Wistar rats.

Authors:  Olubunmi A Wintola; Taofik O Sunmonu; Anthony J Afolayan
Journal:  BMC Gastroenterol       Date:  2010-08-19       Impact factor: 3.067

2.  Changes in colonic motility induced by sennosides in dogs: evidence of a prostaglandin mediation.

Authors:  G Staumont; J Fioramonti; J Frexinos; L Bueno
Journal:  Gut       Date:  1988-09       Impact factor: 23.059

3.  Misoprostol is effective treatment for patients with severe chronic constipation.

Authors:  E E Soffer; A Metcalf; J Launspach
Journal:  Dig Dis Sci       Date:  1994-05       Impact factor: 3.199

Review 4.  Aloe vera Is Effective and Safe in Short-term Treatment of Irritable Bowel Syndrome: A Systematic Review and Meta-analysis.

Authors:  Seung Wook Hong; Jaeyoung Chun; Sunmin Park; Hyun Jung Lee; Jong Pil Im; Joo Sung Kim
Journal:  J Neurogastroenterol Motil       Date:  2018-10-01       Impact factor: 4.924
  4 in total

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