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Literature DB >> 6656986

Determination of pyridoxal phosphate levels in the brains of audiogenic and normal mice.

Abstract

The concentrations of pyridoxal-5'-phosphate in the brains of audiogenic and normal mice were measured fluorimetrically. The brain of the audiogenic mouse (DBA/2J) contains 25% more pyridoxal-5'-phosphate than the brain of a control mouse. Intraperitoneal injection of this substance causes a transient increase of its concentration in the brain, lasting a few hours. The substance thereafter is degraded to pyridoxal and pyridoxic acid.

Entities: Chemical Species

Mesh：

Substances：

Year: 1983 PMID： 6656986 DOI： 10.1007/BF00963995

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

30 in total

1. NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5-PHOSPHATE.

Authors: V BONAVITA; R GUARNERI; P MONACO
Journal: J Neurochem Date: 1964-11 Impact factor: 5.372

2. Effect of vitamin B6 deficiency on the basal and adapted levels of rat liver tyrosine and tryptophan transaminases.

Authors: E C LIN; M CIVEN; W E KNOX
Journal: J Biol Chem Date: 1958-11 Impact factor: 5.157

3. Vitamin B6 and protein synthesis.

Authors: H C LICHSTEIN
Journal: J Biol Chem Date: 1956-03 Impact factor: 5.157

4. Effects of stimulants of the central nervous system on the pyridoxal phosphate content of the rat brain.

Authors: F Bilodeau
Journal: J Neurochem Date: 1965-07 Impact factor: 5.372

Review 5. Reaction pathways and mechanisms of pyridoxal catalysis.

Authors: A E Martell
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1982

Review 6. Analogs of pyridoxal or pyridoxal phosphate: relation of structure to binding with apoenzymes and to catalytic activity.

Authors: E E Snell
Journal: Vitam Horm Date: 1970 Impact factor: 3.421

7. Fluorometric determination of pyridoxal-5-phosphate and pyridoxal in biological materials. II. Specificity of the method in pyridoxal-5-phosphate determination.

Authors: M Yamada; A Saito; Z Tamura
Journal: Chem Pharm Bull (Tokyo) Date: 1966-05 Impact factor: 1.645

Determination of pyridoxal phosphate levels in the brains of audiogenic and normal mice.

1. NEUROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES WITH THE ISONICOTINOYLHYDRAZONE OF PYRIDOXAL 5-PHOSPHATE.

2. Effect of vitamin B6 deficiency on the basal and adapted levels of rat liver tyrosine and tryptophan transaminases.

3. Vitamin B6 and protein synthesis.

4. Effects of stimulants of the central nervous system on the pyridoxal phosphate content of the rat brain.

Review 5. Reaction pathways and mechanisms of pyridoxal catalysis.

Review 6. Analogs of pyridoxal or pyridoxal phosphate: relation of structure to binding with apoenzymes and to catalytic activity.

7. Fluorometric determination of pyridoxal-5-phosphate and pyridoxal in biological materials. II. Specificity of the method in pyridoxal-5-phosphate determination.

8. Metal ion interactions and glutamine synthetase activity.

9. Inhibition of tyrosine aminotransferase activity by low concentrations of urea.

10. Pyridoxal phosphate as the coenzyme of the mammalian decarboxylase for L-cysteine sulphinic and L-cysteic acids.

Review 1. A risk-benefit assessment of treatments for infantile spasms.

2. Current trends in the treatment of infantile spasms.