| Literature DB >> 6656311 |
Abstract
Ductal elongation in young, proliferating mouse mammary gland is associated with a zone of DNA synthesis in stroma surrounding the end buds. In contrast, slowly growing, serially aged tissue fails to elicit a significant elevation of stromal DNA synthetic activity. Since fatty stroma is required for normal mammary growth and morphogenesis, this altered interaction may be a significant factor in the aging of mammary epithelium.Entities:
Mesh:
Year: 1983 PMID: 6656311 DOI: 10.1016/0047-6374(83)90028-3
Source DB: PubMed Journal: Mech Ageing Dev ISSN: 0047-6374 Impact factor: 5.432