Literature DB >> 665610

Effect of histamine H1- and H2-receptor blockade on canine gastric acid secretion.

G O Barbezat, F S Bowey, E R Kaplan, R Hickman.   

Abstract

In dogs with gastric fistulae and Heidenhain pouches, inhibition of histamine-stimulated gastric acid secretion by the histamine H2-receptor antagonist metiamide is not increased by the addition of a histamine H1-receptor antagonist (mepyramine maleate). Under the conditions of this study there is no evidence for the presence of histamine H1-receptor sites on the gastric parietal cell.

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Year:  1978        PMID： 665610     DOI： 10.1007/BF01072321

Source DB:  PubMed          Journal:  Am J Dig Dis        ISSN： 0002-9211


  7 in total

1.  An analysis of the depressor responses to histamine in the cat and dog: involvement of both H1- and H2-receptors.

Authors:  J W Black; D A Owen; M E Parsons
Journal:  Br J Pharmacol       Date:  1975-07       Impact factor: 8.739

2.  The effect of antihistamine substances on gastric secretion in man.

Authors:  C A ASHFORD; H HELLER; G A SMART
Journal:  Br J Pharmacol Chemother       Date:  1949-06

3.  Pharmacology of antihistamine compounds.

Authors:  E R LOEW
Journal:  Physiol Rev       Date:  1947-10       Impact factor: 37.312

4.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

5.  Receptors mediating some actions of histamine.

Authors:  A S Ash; H O Schild
Journal:  Br J Pharmacol Chemother       Date:  1966-08

6.  Inhibition of acid secretion in dog by metiamide, a histamine antagonist acting on H2 receptors.

Authors:  M I Grossman; S J Konturek
Journal:  Gastroenterology       Date:  1974-04       Impact factor: 22.682

7.  Histamine receptors in esophageal smooth muscle of the opossum.

Authors:  D J de Carle; M J Brody; J Christensen
Journal:  Gastroenterology       Date:  1976-06       Impact factor: 22.682
  7 in total
  2 in total

1.  Gastric and cardiovascular effects of histamine in the dog.

Authors:  B I Hirschowitz; J Rentz; E Molina; A L Waldo
Journal:  Agents Actions       Date:  1979-12

2.  The effect of ranitidine on gastric acid secretory response curves to histamine, pentagastrin or bethanechol in the dog with a Heidenhain pouch.

Authors:  M J Daly; J M Humphray; K T Bunce; R Stables
Journal:  Agents Actions       Date:  1981-04
  2 in total

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