Literature DB >> 6655669

The haemoglobin pattern of sickle cell and haemoglobin C beta +-thalassaemia in Liberia.

M Willcox.   

Abstract

Haemoglobin components in 21 Liberians with Hb S beta +-thalassaemia and four with Hb C beta +-thalassaemia were measured to classify the forms of beta +-thalassaemia present in the population. In 20 Hb S and all Hb C beta +-thalassaemics the data were consistent with the interaction of these variants with the mild type 2 (Negro) form of beta +-thalassaemia. The data available were insufficient to classify the remaining case, a young child. It was concluded that the clinically more severe type of beta +-thalassaemia giving Hb A levels of 5 to 15% in compound heterozygotes is probably uncommon in Liberia.

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Year:  1983        PMID： 6655669      PMCID： PMC1049174          DOI： 10.1136/jmg.20.6.430

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  10 in total

1.  Thalassaemia in northern Liberia. A survey in the Mount Nimba area.

Authors:  M C Willcox
Journal:  J Med Genet       Date:  1975-03       Impact factor: 6.318

2.  Homozygous beta thalassaemia in Liberia.

Authors:  M C Willcox; D J Weatherall; J B Clegg
Journal:  J Med Genet       Date:  1975-06       Impact factor: 6.318

3.  BIOCHEMICAL PHENOTYPES OF THALASSEMIA IN THE AMERICAN NEGRO POPULATION.

Authors:  D J WEATHERALL
Journal:  Ann N Y Acad Sci       Date:  1964-10-07       Impact factor: 5.691

4.  The wave of advance of an advantageous gene: the sickle cell gene in Liberia.

Authors:  F B LIVINGSTONE
Journal:  Hum Biol       Date:  1960-05       Impact factor: 0.553

5.  [Demonstration of fetal hemoglobin in erythrocytes of a blood smear].

Authors:  E KLEIHAUER; H BRAUN; K BETKE
Journal:  Klin Wochenschr       Date:  1957-06-15

6.  The distribution of the sickle cell gene in Liberia.

Authors:  F B LIVINGSTONE
Journal:  Am J Hum Genet       Date:  1958-03       Impact factor: 11.025

7.  The clinical features of sickle-cell- thalassaemia in Jamaica.

Authors:  G R Serjeant; M T Ashcroft; B E Serjeant; P F Milner
Journal:  Br J Haematol       Date:  1973-01       Impact factor: 6.998

8.  Reliable routine estimation of small amounts of foetal haemoglobin by alkali denaturation.

Authors:  M E Pembrey; P McWade; D J Weatherall
Journal:  J Clin Pathol       Date:  1972-08       Impact factor: 3.411

9.  Preliminary surveys for the prevalence of the thalassemia genes in some African populations.

Authors:  D J Weatherall; H M Gilles; J B Clegg; J A Blankson; D Mustafa; F S Boi-Doku; D S Chaudhury
Journal:  Ann Trop Med Parasitol       Date:  1971-06

10.  Haemoglobin variants, beta-thalassaemia and G-6-PD types in Liberia.

Authors:  M C Willcox; L Beckman
Journal:  Hum Hered       Date:  1981       Impact factor: 0.444
  10 in total
  1 in total

1.  High School Knowledge and Attitudes towards Thalassemia in Southeastern Iran.

Authors:  Ebrahim Miri-Moghaddam; Eisa Motaharitabar; Leila Erfannia; Alireza Dashipour; Marziyeh Houshvar
Journal:  Int J Hematol Oncol Stem Cell Res       Date:  2014
  1 in total

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