Literature DB >> 6652361

Evidence for a magnesium-sparing action by amiloride during renal clearance studies in rats.

J Devane, M P Ryan.   

Abstract

The potassium-sparing diuretic, amiloride, reduced the fractional excretion of magnesium in anaesthetized rats. Alterations in glomerular filtration rate (GFR), the filtered load of magnesium, arterial blood pressure, the status of the extracellular fluid volume, plasma aldosterone concentration and acid-base balance were not involved. It was concluded that amiloride exerted a magnesium-sparing effect by a direct renal action.

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Year:  1983        PMID： 6652361      PMCID： PMC2044936          DOI： 10.1111/j.1476-5381.1983.tb10533.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  17 in total

1.  Fluormetric method for the determination of magnesium in renal tubular fluid.

Authors:  M G Brunette; M E Crochet
Journal:  Anal Biochem       Date:  1975-05-12       Impact factor: 3.365

2.  Micropuncture study of magnesium transport along the nephron in the young rat.

Authors:  M G Brunette; N Vigneault; S Carriere
Journal:  Am J Physiol       Date:  1974-10

3.  Effects of chlorothiazide and amipramizide (MK 870) on the renal excretion of calcium, phosphate and magnesium.

Authors:  C G Duarte
Journal:  Metabolism       Date:  1968-05       Impact factor: 8.694

4.  Effects of ethacrynic acid and furosemide on urinary calcium, phosphate and magnesium.

Authors:  C G Duarte
Journal:  Metabolism       Date:  1968-10       Impact factor: 8.694

5.  Evidence for renal magnesium secretion during magnesium infusions in the dog.

Authors:  S F Wen; N L Wong; J H Dirks
Journal:  Am J Physiol       Date:  1971-01

6.  [Studies of the effect of the diuretics furosemide, ethacrynic acid and triamterene on renal magnesium and calcium excretion].

Authors:  S Hänze; H Seyberth
Journal:  Klin Wochenschr       Date:  1967-03-15

7.  Magnesium-saving property of an aldosterone antagonist in the treatment of oedema of liver cirrhosis.

Authors:  P Lim; E Jacob
Journal:  Br Med J       Date:  1978-03-25

8.  The renal handling of magnesium.

Authors:  C M Averill; F W Heaton
Journal:  Clin Sci       Date:  1966-12       Impact factor: 6.124

9.  Renin release, an artifact of anesthesia and its implications in rats.

Authors:  W A Pettinger; K Tanaka; K Keeton; W B Campbell; S N Brooks
Journal:  Proc Soc Exp Biol Med       Date:  1975-03

10.  Magnesium deficiency in patients on long-term diuretic therapy for heart failure.

Authors:  P Lim; E Jacob
Journal:  Br Med J       Date:  1972-09-09
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  4 in total

1.  Effects of a new pteridine derivative on urinary sodium, potassium and magnesium excretion in conscious saline-loaded rats.

Authors:  T Netzer; F Ullrich; H Priewer; M Majewski; E Mutschler
Journal:  Br J Pharmacol       Date:  1992-05       Impact factor: 8.739

2.  Absence of magnesium sparing effect of a single dose of triamterene in combination with frusemide in healthy male adults.

Authors:  J J van Meyel; P Smits; F W Gribnau
Journal:  Br J Clin Pharmacol       Date:  1990-11       Impact factor: 4.335

Review 3.  Diuretics. Clinical pharmacology and therapeutic use (Part II).

Authors:  A Lant
Journal:  Drugs       Date:  1985-02       Impact factor: 9.546

Review 4.  Effects of diuretics on the renal handling of magnesium.

Authors:  M P Ryan; J Devane; M F Ryan; T B Counihan
Journal:  Drugs       Date:  1984-10       Impact factor: 9.546
  4 in total

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